Publikationen
Aldejohann AM, Menner C, Thielemann N, Martin R, Walther G, Kurzai O. (2024) In vitro activity of ibrexafungerp against clinically relevant echinocandin-resistant Candida strains. Antimicrob Agents Chemother. 2024 Jan 11:e0132423. doi: 10.1128/aac.01324-23. PMID: 38206004
Banz M, Stallmach A, Gaßler N, Schulze PC, Fritzenwanger M, Cornely O, Kurzai O, Pletz MW. (2024) Fatal pulmonary hemorrhage, pneumothorax and skin necrosis caused by IRIS to an Aspergillus flavus infection in a young patient with metamizole associated agranulocytosis. Infection. 2023 Dec 22. doi: 10.1007/s15010-023-02149-x. PMID: 38133714
Krone M, Rauschenberger V, Blaschke V, Claus H, Kurzai O, Kampmeier S (2024) Ralstonia pickettii bloodstream infections with potential genomic link to internationally distributed contaminated saline solution, Germany, October 2023. Euro Surveill 29(3), 2400010. doi: 10.2807/1560-7917.ES.2024.29.3.2400010. PMID: 38240062
Kurotschka PK, Borgulya G, Bucher E, Endrich I, Figueiras A, Gensichen J, Hay AD, Hapfelmeier A, Kretzschmann C, Kurzai O, Lam TT, Massidda O, Sanftenberg L, Schmiemann G, Schneider A, Simmenroth A, Stark S, Warkentin L, Ebell MH, Gàgyor I; Bavarian Practice-Based Research Network (BayFoNet) (2024) Dipsticks and point-of-care Microscopy to reduce antibiotic use in women with an uncomplicated Urinary Tract Infection (MicUTI): protocol of a randomised controlled pilot trial in primary care. BMJ Open 14(3), e079345. doi: 10.1136/bmjopen-2023-079345. PMID: 38553055
Schrenker B, Zimmermann A, Koch T, Walther G, Martin R, Kampik D, Kurzai O, Theuersbacher J (2024) Polyhexanide based contact lens storage fluids frequently exhibit insufficient antifungal activity against Fusarium species. Int J Med Microbiol 314, 151602. doi: 10.1016/j.ijmm.2024.151602. Epub 2024 Jan 23. PMID: 38280372
Stieber H, Junghanns L, Wilhelm H, Batliner M, Aldejohann AM, Kurzai O, Martin R (2024) The sphingolipid inhibitor myriocin increases Candida auris susceptibility to amphotericin B. Mycoses 67(4), e13723. doi: 10.1111/myc.13723. PMID: 38551121
Aldejohann AM, Menner C, Thielemann N, Martin R, Walther G, Kurzai O. (2024) In vitro activity of ibrexafungerp against clinically relevant echinocandin-resistant Candida strains. Antimicrob Agents Chemother. 2024 Jan 11:e0132423. doi: 10.1128/aac.01324-23. Online ahead of print. PMID: 38206004
Banz M, Stallmach A, Gaßler N, Schulze PC, Fritzenwanger M, Cornely O, Kurzai O, Pletz MW. (2023) Fatal pulmonary hemorrhage, pneumothorax and skin necrosis caused by IRIS to an Aspergillus flavus infection in a young patient with metamizole associated agranulocytosis. Infection. 2023 Dec 22. doi: 10.1007/s15010-023-02149-x. Online ahead of print. PMID: 38133714
Knies K, Wagenhäuser I, Hofmann D, Rauschenberger V, Eisenmann M, Reusch J, Flemming S, Andres O, Petri N, Topp MS, Papsdorf M, McDonogh M, Verma-Führing R, Scherzad A, Zeller D, Böhm H, Gesierich A, Seitz AK, Kiderlen M, Gawlik M, Taurines R, Wurmb T, Ernestus RI, Forster J, Weismann D, Weißbrich B, Liese J, Vogel U, Kurzai O, Dölken L, Gabel A, Krone M. (2023) The Sensitivity of Rapid Tests for SARS-CoV-2 Antigen. Dtsch Arztebl Int. 2023 Nov 10;120(45):763-764. doi: 10.3238/arztebl.m2023.0185. PMID: 38051563 Free PMC article.
Sartawi Z, Blackshields C, Ariamanesh A, Farag FF, Griffin B, Crean A, Devine K, Elkhashab M, Aldejohann AM, Kurzai O, Faisal W. (2023) Glass Microneedles: A Case Study for Regulatory Approval Using a Quality by Design Approach. Adv Mater. 2023 Dec;35(52):e2305834. doi: 10.1002/adma.202305834. Epub 2023 Nov 21. PMID: 37950607
Aldejohann AM, Martin R, Hecht J, Haller S, Rickerts V, Walther G, Eckmanns T, Kurzai O. (2023) Rise in Candida Auris Cases and First Nosocomial Transmissions in Germany. Dtsch Arztebl Int. 2023 Jul 10;120(27-28):447-478. doi: 10.3238/arztebl.m2023.0047. PMID: 37661316 Free article.
Wagenhäuser I, Mees J, Reusch J, Lâm TT, Schubert-Unkmeir A, Krone LB, Frey A, Kurzai O, Frantz S, Dölken L, Liese J, Gabel A, Petri N, Krone M. (2023) Determinants of Influenza A infection rate in post-COVID-19 era. J Infect. 2023 Oct;87(4):361-364. doi: 10.1016/j.jinf.2023.08.003. Epub 2023 Aug 9. PMID: 37567511
Reusch J, Wagenhäuser I, Gabel A, Höhn A, Lâm TT, Krone LB, Frey A, Schubert-Unkmeir A, Dölken L, Frantz S, Kurzai O, Vogel U, Krone M, Petri N. (2023) Inability to work following COVID-19 vaccination-a relevant aspect for future booster vaccinations. Public Health. 2023 Sep;222:186-195. doi: 10.1016/j.puhe.2023.07.008. Epub 2023 Aug 8. PMID: 37562083
Mirhakkak MH, Chen X, Ni Y, Heinekamp T, Sae-Ong T, Xu LL, Kurzai O, Barber AE, Brakhage AA, Boutin S, Schäuble S, Panagiotou G. (2023) Genome-scale metabolic modeling of Aspergillus fumigatus strains reveals growth dependencies on the lung microbiome. Nat Commun. 2023 Jul 20;14(1):4369. doi: 10.1038/s41467-023-39982-5. PMID: 37474497 Free PMC article.
Weiß M, Gründahl M, Deckert J, Eichner FA, Kohls M, Störk S, Heuschmann PU, Hein G; STAAB-COVID Study Group. (2023) Differential network interactions between psychosocial factors, mental health, and health-related quality of life in women and men. Sci Rep. 2023 Jul 19;13(1):11642. doi: 10.1038/s41598-023-38525-8. PMID: 37468704 Free PMC article.
Häder A, Schäuble S, Gehlen J, Thielemann N, Buerfent BC, Schüller V, Hess T, Wolf T, Schröder J, Weber M, Hünniger K, Löffler J, Vylkova S, Panagiotou G, Schumacher J, Kurzai O. (2023) Pathogen-specific innate immune response patterns are distinctly affected by genetic diversity. Nat Commun. 2023 Jun 5;14(1):3239. doi: 10.1038/s41467-023-38994-5. PMID: 37277347
Wiese-Posselt M, Lâm TT, Schröder C, Schneider S, Kurzai O, Feufel MA, Gastmeier P. (2023) Appropriate antibiotic use and antimicrobial resistance: knowledge, attitudes and behaviour of medical students and their needs and preferences for learning. Antimicrob Resist Infect Control. 2023 May 17;12(1):48. doi: 10.1186/s13756-023-01251-x. PMID: 37198699
Wagenhäuser I, Reusch J, Gabel A, Mees J, Nyawale H, Frey A, Lâm TT, Schubert-Unkmeir A, Dölken L, Kurzai O, Frantz S, Petri N, Krone M, Krone LB. (2023) The relationship between mental health, sleep quality and the immunogenicity of COVID-19 vaccinations. J Sleep Res. 2023 May 13:e13929. doi: 10.1111/jsr.13929. PMID: 37177872
Garbe E, Thielemann N, Hohner S, Kumar A, Vylkova S, Kurzai O, Martin R. (2023) Functional analysis of the Candida albicans ECE1 Promoter. Microbiol Spectr. 2023 Feb 14;11(2):e0025323. doi: 10.1128/spectrum.00253-23. PMID: 36786567
Engels G, Hecker K, Forster J, Toepfner N, Hick E, Pietsch F, Heuschmann P, Berner R, Härtel C, Kurzai O, Petersmann A, Streng A, Liese J. (2022) High Seroprevalence of SARS-CoV-2 in Preschool Children in July 2022. Dtsch Arztebl Int. 2022 Nov 11;119(45):771-772. doi: 10.3238/arztebl.m2022.0345. PMID: 36700368
Wagenhäuser I, Reusch J, Gabel A, Krone LB, Kurzai O, Petri N, Krone M. (2023) Bivalent BNT162b2 mRNA original/omicron BA.4-5 booster vaccination: adverse reactions and inability to work compared with the monovalent COVID-19 booster. Clin Microbiol Infect. 2023 Apr;29(4):554-556. doi: 10.1016/j.cmi.2023.01.008. Epub 2023 Jan 16. PMID: 36657489
Krone M, Wagenhäuser I, Knies K, Hofmann D, Engels G, Taurines R, McDonogh M, Flemming S, Meyer T, Böhm H, Scherzad A, Eisenmann M, Rauschenberger V, Gabel A, Petri N, Reusch J, Forster J, Weißbrich B, Dölken L, Kurzai O, Vogel U, Härtel C, Liese J, Andres O. (2023) Clinical accuracy of SARS-CoV-2 rapid antigen testing in screening children and adolescents. J Infect. 2023 Mar;86(3):256-308. doi: 10.1016/j.jinf.2022.12.017. Epub 2022 Dec 21. PMID: 36565725
Wagenhäuser I, Reusch J, Gabel A, Höhn A, Lâm TT, Almanzar G, Prelog M, Krone LB, Frey A, Schubert-Unkmeir A, Dölken L, Frantz S, Kurzai O, Vogel U, Petri N, Krone M. (2023) Immunogenicity and safety of coadministration of COVID-19 and influenza vaccination. Eur Respir J. 2023 Jan 6;61(1):2201390. doi: 10.1183/13993003.01390-2022. PMID: 36549716
Papan C, Geipel M, Heidtmann S, Müller R, Praschmo D, Meier CM, Walther G, Kurzai O, Groll AH, Zemlin M, Simon A. (2023) A mould in the fold should never grow old: cutaneous aspergillosis in a preterm neonate. Clin Microbiol Infect. 2023 Mar;29(3):338-339. doi: 10.1016/j.cmi.2022.10.027. Epub 2022 Oct 29. PMID: 36404482
Kohlenberg A, Monnet DL, Plachouras D; Candida auris survey collaborative group; Candida auris survey collaborative group includes the following national experts. (2022) Increasing number of cases and outbreaks caused by Candida auris in the EU/EEA, 2020 to 2021. Euro Surveill. 2022 Nov;27(46):2200846. doi: 10.2807/1560-7917.ES.2022.27.46.2200846. PMID: 36398575 Free PMC article.
Engels G, Oechsle AL, Schlegtendal A, Maier C, Holzwarth S, Streng A, Lange B, Karch A, Petersmann A, Streeck H, Blaschke-Steinbrecher S, Härtel C, Schroten H, von Kries R, Berner R, Liese J, Brinkmann F, Toepfner N (2023) SARS-CoV-2 sero-immunity and quality of life in children and adolescents in relation to infections and vaccinations: the IMMUNEBRIDGE KIDS cross-sectional study, 2022. Infection, 1-9.
Kurzai O, Claus H, Lâm TT (2023) Obituary Prof. Ulrich Vogel, MD 1964-2022: a scientific mentor and expert in infection prevention and control. Med Microbiol Immunol 212(1), 1-2. (Review)
Reusch J, Wagenhäuser I, Gabel A, Eggestein A, Höhn A, Lâm TT, Frey A, Schubert-Unkmeir A, Dölken L, Frantz S, Kurzai O, Vogel U, Krone M, Petri N (2023) Influencing factors of anti-SARS-CoV-2-spike-IgG antibody titers in healthcare workers: A cross-section study. J Med Virol 95(1), e28300.
Wagenhäuser I, Knies K, Hofmann D, Rauschenberger V, Eisenmann M, Reusch J, Gabel A, Flemming S, Andres O, Petri N, Topp MS, Papsdorf M, McDonogh M, Verma-Führing R, Scherzad A, Zeller D, Böhm H, Gesierich A, Seitz AK, Kiderlen M, Gawlik M, Taurines R, Wurmb T, Ernestus RI, Forster J, Weismann D, Weißbrich B, Dölken L, Liese J, Kaderali L, Kurzai O, Vogel U, Krone M (2023) Virus variant-specific clinical performance of SARS coronavirus two rapid antigen tests in point-of-care use, from November 2020 to January 2022. Clin Microbiol Infect 29(2):225-232.
Aldejohann AM, Wiese-Posselt M, Gastmeier P, Kurzai O (2022) Expert recommendations for prevention and management of Candida auris transmission. Mycoses 65(6), 590-598. (Review)
Belyaev I*, Marolda A*, Praetorius JP, Sarkar A, Medyukhina A, Hünniger K, Kurzai O, Figge MT (2022) Automated characterisation of neutrophil activation phenotypes in ex vivo human Candida blood infections. Comput Struct Biotechnol J 20, 2297-2308.
Bloos F, Held J, Kluge S, Simon P, Kogelmann K, de Heer G, Kuhn SO, Jarczak D, Motsch J, Hempel G, Weiler N, Weyland A, Drüner M, Gründling M, Meybohm P, Richter D, Jaschinski U, Moerer O, Günther U, Schädler D, Weiss R, Putensen C, Castellanos I, Kurzai O, Schlattmann P, Cornely OA, Bauer M, Thomas-Rüddel D (2022) (1 → 3)-β-D-Glucan-guided antifungal therapy in adults with sepsis: the CandiSep randomized clinical trial. Intensive Care Med 48(7), 865-875.
Engels G, Forster J, Streng A, Rücker V, Rudolph P, Pietsch F, Wallstabe J, Wallstabe L, Krauthausen M, Schmidt J, Ludwig T, Bauer C, Gierszewski D, Bendig J, Timme S, Jans T, Weißbrich B, Romanos M, Dölken L, Heuschmann P, Härtel C, Gágyor I, Figge MT, Liese J, Kurzai O (2022) Acceptance of different self-sampling methods for semiweekly SARS-CoV-2 testing in asymptomatic children and childcare workers at German Day Care Centers: A nonrandomized controlled trial. JAMA Netw Open 5(9), e2231798.
Engels G, Hecker K, Forster J, Toepfner N, Hick E, Pietsch F, Heuschmann P, Berner R, Härtel C, Kurzai O, Petersmann A, Streng A, Liese J. (2022) High Seroprevalence of SARS-CoV-2 in Preschool Children in July 2022. Dtsch Arztebl Int. 2022 Nov 11;119(45):771-772. doi: 10.3238/arztebl.m2022.0345.
Forster J, Koc Ö, Koeppel MB, Hamprecht A, Kurzai O, Suerbaum S, Wagener J, Dichtl K (2022) β-1,3-D-glucan and galactomannan as biomarkers for the detection of invasive Geotrichum and Magnusiomyces infections: a retrospective evaluation. J Clin Microbiol 60(1), e0160721.
Forster J, Streng A, Rudolph P, Rücker V, Wallstabe J, Timme S, Pietsch F, Hartmann K, Krauthausen M, Schmidt J, Ludwig T, Gierszewski D, Jans T, Engels G, Weißbrich B, Romanos M, Dölken L, Heuschmann P, Härtel C, Gágyor I, Figge MT, Kurzai O, Liese J (2022) Feasibility of SARS-CoV-2 surveillance testing among children and childcare workers at German Day Care Centers: A nonrandomized controlled trial. JAMA Netw Open 5(1), e2142057.
Fuchs F, Aldejohann AM, Hoffmann AM, Walther G, Kurzai O, Hamprecht AG (2022) In vitro activity of nitroxoline in antifungal-resistant Candida species isolated from the urinary tract. Antimicrob Agents Chemother 66(6), e0226521.
Gierszewski D, Kurotschka PK, Krauthausen M, Fröhlich W, Forster J, Pietsch F, Streng A, Rücker V, Wallstabe J, Hartmann K, Jans T, Engels G, Romanos M, Heuschmann P, Härtel C, Kurzai O, Liese J, Gágyor I (2022) Parents' and childcare workers' perspectives toward SARS-CoV-2 test and surveillance protocols in pre-school children day care centers: A qualitative study within the German Wü-KiTa-CoV project. Front Med (Lausanne) 9, 897726.
Gierszewski D, Kurotschka PK, Krauthausen M, Fröhlich W, Forster J, Pietsch F, Streng A, Rücker V, Wallstabe J, Hartmann K, Jans T, Engels G, Romanos M, Heuschmann P, Härtel C, Kurzai O, Liese J, Gágyor I (2022) Corrigendum: Parents' and childcare workers' perspectives toward SARS-CoV-2 test and surveillance protocols in pre-school children day care centers: A qualitative study within the german Wü-KiTa-CoV project. Front Med (Lausanne) 9, 973518.
Hinrichs C, Wiese-Posselt M, Graf B, Geffers C, Weikert B, Enghard P, Aldejohann A, Schrauder A, Knaust A, Eckardt KU, Gastmeier P, Kurzai O (2022) Successful control of Candida auris transmission in a German COVID-19 intensive care unit. Mycoses 65(6), 643-649.
Koehler P, von Stillfried S, Garcia Borrega J, Fuchs F, Salmanton-García J, Pult F, Böll B, Eichenauer DA, Shimabukuro-Vornhagen A, Kurzai O, Boor P, Kochanek M, Cornely OA (2022) Aspergillus tracheobronchitis in COVID-19 ARDS patients - a cohort study. Eur Respir J 59(5), 2103142.
Kohlenberg A, Monnet DL, Plachouras D, Candida auris survey collaborative group; Candida auris survey collaborative group includes the following national experts. (2022) Increasing number of cases and outbreaks caused by Candida auris in the EU/EEA, 2020 to 2021. Euro Surveill 27(46), 2200846.
Noster J, Köppel M, Desnos-Ollivier M, Aigner M, Bader O, Dichtl K, Göttig S, Haas A, Kurzai O, Pranada A, Stelzer Y, Walther G, Hamprecht A (2022) Bloodstream infections caused by Magnusiomyces capitatus and Magnusiomyces clavatus: epidemiological, clinical and microbiological features of two emerging yeast species. Antimicrob Agents Chemother 66(2), e0183421.
Papan C, Geipel M, Heidtmann S, Müller R, Praschmo D, Meier CM, Walther G, Kurzai O, Groll AH, Zemlin M, Simon A (2022) A mould in the fold should never grow old: cutaneous aspergillosis in a preterm neonate. Clin Microbiol Infect 29(3), 338-339.
Rogers TR, Verweij PE, Castanheira M, Dannaoui E, White PL, Arendrup MC (2022) Molecular mechanisms of acquired antifungal drug resistance in principal fungal pathogens and EUCAST guidance for their laboratory detection and clinical implications. J Antimicrob Chemother 77(8), 2053-2073. (Review)
Rohde J, Himmel W, Hofinger C, Lâm TT, Schrader H, Wallstabe J, Kurzai O, Gágyor I (2022) Diagnostic accuracy and feasibility of a rapid SARS-CoV-2 antigen test in general practice - a prospective multicenter validation and implementation study. BMC Prim Care 23(1), 149.
Rohner S, Morell M, Wohlsein P, Stürznickel J, Reiter EB, Jahnke A, Prenger-Berninghoff E, Ewers C, Walther G, Striewe LC, Virgilio Failla A, Siebert U (2022) Fatal aspergillosis and evidence of unrelated hearing loss in a harbor porpoise (Phocoena phocoena) from the German Baltic Sea. Front Mar Sci 9, 958019.
Seidel D, Simon M, Sprute R, Lubnow M, Evert K, Speer C, Seeßle J, Khatamzas E, Merle U, Behrens C, Blau IW, Enghard P, Haas CS, Steinmann J, Kurzai O, Cornely OA (2022) Results from a national survey on COVID-19-associated mucormycosis in Germany: 13 patients from six tertiary hospitals. Mycoses 65(1), 103-109.
Seif M, Kakoschke TK, Ebel F, Bellet MM, Trinks N, Renga G, Pariano M, Romani L, Tappe B, Espie D, Donnadieu E, Hünniger K, Häder A, Sauer M, Damotte D, Alifano M, White PL, Backx M, Nerreter T, Machwirth M, Kurzai O, Prommersberger S, Einsele H, Hudecek M, Löffler J (2022) CAR T cells targeting Aspergillus fumigatus are effective at treating invasive pulmonary aspergillosis in preclinical models. Sci Transl Med 14(664), eabh1209.
Tappe B, Lauruschkat C, Strobel L, Kurzai O, Rebhan S, Kraus S, Lauruschkat C, Garcia JP, Bussemer L, Possler L, Held M, Huenniger K, Kniemeyer O, Schäuble S, Brakhage AA, Panagiotou G, White L, Einsele H, Löffler J, Wurster S (2022) COVID-19 patients share common, corticosteroid-independent features of impaired host immunity to pathogenic molds. Front Immunol 13, 954985.
Thielemann N, Herz M, Kurzai O, Martin R (2022) Analyzing the human gut mycobiome - A short guide for beginners. Comput Struct Biotechnol J 20, 608-614. (Review)
Thomas-Rüddel D, Schlattmann P, Pletz M, Kurzai O, Bloos F (2022) Risk factors for invasive Candida infection in critically ill patients - a systematic review and meta-analysis. Chest 161(2), 345. (Review)
Wagenhäuser I, Knies K, Hofmann D, Rauschenberger V, Eisenmann M, Reusch J, Gabel A, Flemming S, Andres O, Petri N, Topp MS, Papsdorf M, McDonogh M, Verma-Führing R, Scherzad A, Zeller D, Böhm H, Gesierich A, Seitz AK, Kiderlen M, Gawlik M, Taurines R, Wurmb T, Ernestus RI, Forster J, Weismann D, Weißbrich B, Dölken L, Liese J, Kaderali L, Kurzai O, Vogel U, Krone M (2022) Virus variant-specific clinical performance of SARS coronavirus two rapid antigen tests in point-of-care use, from November 2020 to January 2022. Clin Microbiol Infect 29(2), 225-232.
Zoran T, Seelbinder B, White PL, Price JS, Kraus S, Kurzai O, Linde J, Häder A, Loeffler C, Grigoleit GU, Einsele H, Panagiotou G, Loeffler J, Schäuble S (2022) Molecular profiling reveals characteristic and decisive signatures in patients after allogeneic stem cell transplantation suffering from invasive pulmonary aspergillosis. J Fungi (Basel) 8(2), 171.
Aldejohann AM, Herz M, Martin R, Walther G, Kurzai O (2021) Emergence of resistant Candida glabrata in Germany. JAC Antimicrob Resist 3(3), dlab122.
Aldejohann AM, Theuersbacher J, Haug L, Lamm OS, Walther G, Kurzai O, Hillenkamp J, Kampik D (2021) First case of Kluyveromyces marxianus (Candida kefyr) late onset keratitis after lamellar endothelial corneal graft. Med Mycol Case Rep 32, 21-24.
Barber AE*, Sae-Ong T*, Kang K, Seelbinder S, Li J, Walther G, Panagiotou G# & Kurzai O# (2021) Aspergillus fumigatus pan-genome analysis identifies genetic variants associated with human infection Nat Microbiol 6, 1526-1536.
Eichner FA, Gelbrich G, Weißbrich B, Dölken L, Kurzai O, Deckert J, Ertl G, Barth M, Hein G, Neuhauser H, Morbach C, Störk S, Heuschmann P (2021) [Seroprevalence of COVID-19 and psychosocial effects in the general population: Results of the STAAB-COVID-one program]. Gesundheitswesen 83(12), 965-975.
Forster J, Koc Ö, Koeppel MB, Hamprecht A, Kurzai O, Suerbaum S, Wagener J, Dichtl K (2021) β-1,3-D-glucan and galactomannan as biomarkers for the detection of invasive Geotrichum and Magnusiomyces infections: a retrospective evaluation. J Clin Microbiol 60(1), e0160721.
Fuchs F, Hof H, Hofmann S, Kurzai O, Meis JF, Hamprecht A (2021) Antifungal activity of nitroxoline against Candida auris isolates. Clin Microbiol Infect S1198-743X(21), 00366-9.
Groll AH, Gordon K, Buchheidt D, Willinger B, Heinz WJ, Kurzai O, Rickerts V, Cornely OA - Medical Mycology at German Academic Medical Centers (MMGAMC) Study Group (2021) State of Medical Mycology at German Academic Medical Centres: A survey of the German-Speaking Mycological Society (DMYKG) and the Paul-Ehrlich-Society for Chemotherapy (PEG). Mycoses doi: 10.1111/myc.13346.
Jiao C, Sharma S, Dugar G, Peeck NL, Bischler T, Wimmer F, Yu Y, Barquist L, Schoen C, Kurzai O, Sharma CM, Beisel CL (2021) Noncanonical crRNAs derived from host transcripts enable multiplexable RNA detection by Cas9. Science 372(6545), 941-948.
Krone M, Gütling J, Wagener J, Lâm TT, Schoen C, Vogel U, Stich A, Wedekink F, Wischhusen J, Kerkau T, Beyersdorf N, Klingler S, Backes S, Dölken L, Gasteiger G, Kurzai O, Schubert-Unkmeir A (2021) Performance of Three SARS-CoV-2 Immunoassays, Three Rapid Lateral Flow Tests, and a Novel Bead-Based Affinity Surrogate Test for the Detection of SARS-CoV-2 Antibodies in Human Serum J Clin Microbiol 59(8), e0031921.
Lehnert T, Prauße MTE, Hünniger K, Praetorius J-P, Kurzai O, Figge MT (2021) Comparative assessment of immune evasion mechanisms in human whole-blood infection assays by a systems biology approach. PLOS One 16(4), e0249372.
Lehnert T*, Leonhardt I*, Timme S, Thomas-Rüddel D, Bloos F, Sponholz C, Kurzai O, Figge MT#, Hünniger K# (2021) Ex vivo immune profiling in patient blood enables quantification of innate immune effector functions. Sci Rep 11(1), 12039. *equal contribution, #corresponding author
Loos D, Zhang L, Beemelmanns C, Kurzai O, Panagiotou G (2021) DAnIEL: A user-friendly web server for fungal ITS amplicon sequencing data. Front Microbiol 12, 720513.
Machata S, Sreekantapuram S, Hünniger K, Kurzai O, Dunker C, Schubert S, Schulze-Richter B, Speth C, Rambach G, Jacobsen ID (2021) Significant differences in host-pathogen interactions between murine and human whole blood. Front Immunol 11, 565869.
Mottola A, Ramírez-Zavala B, Hünniger K, Kurzai O, Morschhäuser J (2021) The zinc cluster transcription factor Czf1 regulates cell wall architecture and integrity in Candida albicans. Mol Microbiol 116(2), 483-497.
Noster J, Köppel M, Desnos-Ollivier M, Aigner M, Bader O, Dichtl K, Göttig S, Haas A, Kurzai O, Pranada A, Stelzer Y, Walther G, Hamprecht A (2021) Bloodstream infections caused by Magnusiomyces capitatus and Magnusiomyces clavatus: epidemiological, clinical and microbiological features of two emerging yeast species. Antimicrob Agents Chemother 66(2), e0183421.
Roth M, Holtmann C, Daas L, Kakkassery V, Kurzai O, Geerling G, Bäurle S, Bayoudh W, Brücher V, Cvetkova-Fischer N, Dias Blak M, Bornstein A, Fischer C, Fuest M, Grisanti S, Herwig-Carl M, Kroll S, Lenk J, Lommatzsch C, MacKenzie C, Matthaei M, Mehlan J, Messmer E, Müller V, Pawlik V, Ranjbar M, Renner-Wilde A, Rickmann A, Saeger M, Schargus M, Schwarz L, Seitz B, Steindor F, Unterlauf JD, Viestenz A, von Lilienfeld-Toal M, Walther G (2021) Results from the German fungal keratitis registry: Significant differences between cases with and without a history of contact lens use. Cornea 40(11), 1453-1461.
Sattler J, Noster J, Brunke A, Plum G, Wiegel P, Kurzai O, Meis JF, Hamprecht A (2021) Comparison of two commercially available qPCR kits for the detection of Candida auris. J Fungi (Basel) 7(2), 154.
Schneitler S, Bub F, Benthien S, Lepper PM, Kurzai O, Becker SL, Roth S (2021) Floating fungus balls in a blood culture bottle. Clin Microbiol Infect S1198-743X(21), 00096-3.
Seidel D, Simon M, Sprute R, Lubnow M, Evert K, Speer C, Seeßle J, Khatamzas E, Merle U, Behrens C, Blau IW, Enghard P, Haas CS, Steinmann J, Kurzai O, Cornely OA (2021) Results from a national survey on COVID-19-associated mucormycosis in Germany: 13 patients from six tertiary hospitals. Mycoses 65(1), 103-109.
Siscar-Lewin S, Gabaldón T, Aldejohann AM, Kurzai O, Hube B, Brunke S (2021) Transient mitochondria dysfunction confers fungal cross-resistance against phagocytic killing and fluconazole. mBio 12(3), e0112821.
Springer J, Held J, Mengoli C, Schlegel PG, Gamon F, Träger J, Kurzai O, Einsele H, Loeffler J, Eyrich M (2021) Diagnostic performance of (1→3)-β-D-glucan alone and in combination with Aspergillus PCR and galactomannan in serum of pediatric patients after allogeneic hematopoietic stem cell transplantation. J Fungi (Basel) 7(3), 238.
Thomas-Rüddel D, Schlattmann P, Pletz M, Kurzai O, Bloos F (2021) Risk factors for invasive candida infection in critically ill patients - a systematic review and meta-analysis. Chest S0012-3692(21), 04112-X.
Vaezi A, Walther G, Kurzai O, Mahdi D, Dadashzadeh M, Nasri E, Diba K, Badali H, Fakhim H (2021) Frequency of occurrence, seasonal variation and antifungal susceptibility of opportunistic Mucorales isolated from hospital soils in Iran. Mycoses 64(7), 780-787.
Wagenhäuser I, Knies K, Rauschenberger V, Eisenmann M, McDonogh M, Petri N, Andres O, Flemming S, Gawlik M, Papsdorf M, Taurines R, Böhm H, Forster J, Weismann D, Weißbrich B, Dölken L, Liese J, Kurzai O, Vogel U, Krone M (2021) Clinical performance evaluation of SARS-CoV-2 rapid antigen testing in point of care usage in comparison to RT-qPCR. EBioMedicine 69, 103455.
Walther G, Zimmermann A, Theuersbacher J, Kaerger K, von Lilienfeld-Toal M, Roth M, Kampik D, Geerling G, Kurzai O (2021) Eye infections caused by filamentous fungi: Spectrum and antifungal susceptibility of the prevailing agents in germany. J Fungi (Basel) 7(7), 511.
Apsemidou A, Füller MA, Idelevich EA, Kurzai O, Tragiannidis A, Groll AH. (2020) Candida lusitaniae Breakthrough Fungemia in an Immuno-Compromised Adolescent: Case Report and Review of the Literature. J Fungi (Basel). 6(4):380. doi: 10.3390/jof6040380.
von Müller C, Bulman F, Wagner L, Rosenberger D, Marolda A, Kurzai O, Eißmann P, Jacobsen ID, Perner B, Hemmerich P, Vylkova S. (2020) Active neutrophil responses counteract Candida albicans burn wound infection of ex vivo human skin explants. Sci Rep. 10(1):21818. doi: 10.1038/s41598-020-78387-y.
Barber AE, Riedel J, Sae-Ong T, Kang K, Brabetz W, Panagiotou G, Deising HB, Kurzai O. (2020) Effects of Agricultural Fungicide Use on Aspergillus fumigatus Abundance, Antifungal Susceptibility, and Population Structure. mBio. 11(6):e02213-20. doi: 10.1128/mBio.02213-20.
Geiser DM, Al-Hatmi A, Aoki T, Arie T, Balmas V, Barnes I, Bergstrom GC, Bhattacharyya MKK, Blomquist CL, Bowden R, Brankovics B, Brown DW, Burgess LW, Bushley K, Busman M, Cano-Lira JF, Carrillo JD, Chang HX, Chen CY, Chen W, Chilvers MI, Chulze SN, Coleman JJ, Cuomo CA, de Beer ZW, de Hoog GS, Del Castillo-Múnera J, Del Ponte E, Diéguez-Uribeondo J, Di Pietro A, Edel-Hermann V, Elmer WH, Epstein L, Eskalen A, Esposto MC, Everts KL, Fernández-Pavía SP, da Silva GF, Foroud NA, Fourie G, Frandsen RJN, Freeman S, Freitag M, Frenkel O, Fuller KK, Gagkaeva T, Gardiner DM, Glenn AE, Gold S, Gordon T, Gregory NF, Gryzenhout M, Guarro J, Gugino B, Gutiérrez S, Hammond-Kosack K, Harris LJ, Homa M, Hong CF, Hornok L, Huang JW, Ilkit M, Jacobs A, Jacobs K, Jiang C, Jimenez-Gasco MDM, Kang S, Kasson MT, Kazan K, Kennell JC, Kim H, Kistler HC, Kuldau GA, Kulik T, Kurzai O, Laraba I, Laurence MH, Lee TY, Lee YW, Lee YH, Leslie JF, Liew ECY, Lofton LW, Logrieco A, Sánchez López-Berges M, Luque AG, Lysøe E, Ma LJ, Marra RE, Martin FN, May SR, McCormick S, McGee CT, Meis JF, Migheli Q, Mohamed Nor NMI, Monod M, Moretti A, Mostert D, Mulé G, Munaut F, Munkvold GP, Nicholson P, Nucci M, O'Donnell K, Pasquali M, Pfenning LH, Prigitano A, Proctor R, Ranque S, Rehner S, Rep M, Rodríguez-Alvarado G, Rose LJ, Roth MG, Ruiz-Roldán C, Saleh AA, Salleh B, Sang H, Scandiani M, Scauflaire J, Schmale D 3rd, Short DP, Šišić A, Smith J, Smyth CW, Son H, Spahr E, Stajich JE, Steenkamp E, Steinberg C, Subramaniam R, Suga H, Summerell BA, Susca A, Swett CL, Toomajian C, Torres-Cruz TJ, Tortorano AM, Urban M, Vaillancourt LJ, Vallad GE, van der Lee T, Vanderpool D, van Diepeningen AD, Vaughan M, Venter E, Vermeulen M, Verweij PE, Viljoen A, Waalwijk C, Wallace EC, Walther G, Wang J, Ward T, Wickes B, Wiederhold NP, Wingfield MJ, Wood AKM, Xu JR, Yang XB, Yli-Matilla T, Yun SH, Zakaria L, Zhang H, Zhang N, Zhang S, Zhang X. (2020) Phylogenomic analysis of a 55.1 kb 19-gene dataset resolves a monophyletic Fusarium that includes the Fusarium solani Species Complex. Phytopathology. doi: 10.1094/PHYTO-08-20-0330-LE. Online ahead of print.
Seif M, Häder A, Löffler J, Kurzai O (2020) From bench to bedside - translational approaches in anti-fungal immunology. Curr Opin Microbiol. 12;58:153-159. doi: 10.1016/j.mib.2020.10.004.
Wagner L, Stielow JB, de Hoog GS, Bensch K, Schwartze VU, Voigt K, Alastruey-Izquierdo A, Kurzai O, Walther G. (2020) A new species concept for the clinically relevant Mucor circinelloides complex. Persoonia. 44:67-97. doi: 10.3767/persoonia.2020.44.03. Epub 2019 Aug 29.
Kämmer P, McNamara S, Wolf T, Conrad T, Allert S, Gerwien F, Hünniger K, Kurzai O, Guthke R, Hube B, Linde J, Brunke S. (2020) Survival Strategies of Pathogenic Candida Species in Human Blood Show Independent and Specific Adaptations. mBio. 11(5):e02435-20. doi: 10.1128/mBio.02435-20.PMID: 33024045
Weiss E, Schlegel J, Terpitz U, Weber M, Linde J, Schmitt AL, Hünniger K, Marischen L, Gamon F, Bauer J, Löffler C, Kurzai O, Morton CO, Sauer M, Einsele H, Loeffler J. (2020) Reconstituting NK Cells After Allogeneic Stem Cell Transplantation Show Impaired Response to the Fungal Pathogen Aspergillus fumigatus. Front Immunol. 11:2117. doi: 10.3389/fimmu.2020.02117. eCollection 2020.PMID: 33013893
von Jagow B, Kurzai O, Kakkassery V. (2020) Case Report: Beyond the Blood-retina Barrier: Intravitreal Caspofungin for Fungal Endophthalmitis. Optom Vis Sci. 97(7):473-476. doi: 10.1097/OPX.0000000000001532.PMID: 32697551
Hagemann JB, Furitsch M, Wais V, Bunjes D, Walther G, Kurzai O, Essig A. (2020) First case of fatal Rhizomucor miehei endocarditis in an immunocompromised patient. Diagn Microbiol Infect Dis. 98(2):115106. doi: 10.1016/j.diagmicrobio.2020.115106. Epub 2020 Jun 10.PMID: 32629298
Arend N, Pittner A, Ramoji A, Mondol AS, Dahms M, Rüger J, Kurzai O, Schie IW, Bauer M, Popp J, Neugebauer U. (2020) Detection and Differentiation of Bacterial and Fungal Infection of Neutrophils from Peripheral Blood Using Raman Spectroscopy. Anal Chem. 92(15):10560-10568. doi: 10.1021/acs.analchem.0c01384. Epub 2020 Jul 23.PMID: 32613830
Arendrup MC, Friberg N, Mares M, Kahlmeter G, Meletiadis J, Guinea J; Subcommittee on Antifungal Susceptibility Testing (AFST) of the ESCMID European Committee for Antimicrobial Susceptibility Testing (EUCAST). (2020) How to interpret MICs of antifungal compounds according to the revised clinical breakpoints v. 10.0 European committee on antimicrobial susceptibility testing (EUCAST) Clin Microbiol Infect. 2020 Jun 17:S1198-743X(20)30347-5. doi: 10.1016/j.cmi.2020.06.007. Online ahead of print.PMID: 32562861
Barber AE, Scheufen S, Walther G, Kurzai O, Schmidt V. (2020) Low rate of azole resistance in cases of avian aspergillosis in Germany. Med Mycol. 2020 Jun 4:myaa045. doi: 10.1093/mmy/myaa045. Online ahead of print.PMID: 32497229
Ruben S, Garbe E, Mogavero S, Albrecht-Eckardt D, Hellwig D, Häder A, Krüger T, Gerth K, Jacobsen ID, Elshafee O, Brunke S, Hünniger K, Kniemeyer O, Brakhage AA, Morschhäuser J, Hube B, Vylkova S, Kurzai O, Martin R. (2020) Ahr1 and Tup1 Contribute to the Transcriptional Control of Virulence-Associated Genes in Candida albicans. mBio. 11(2). pii: e00206-20. doi: 10.1128/mBio.00206-20.
Chow NA, Muñoz JF, Gade L, Berkow EL, Li X, Welsh RM, Forsberg K, Lockhart SR, Adam R, Alanio A, Alastruey-Izquierdo A, Althawadi S, Araúz AB, Ben-Ami R, Bharat A, Calvo B, Desnos-Ollivier M, Escandón P, Gardam D, Gunturu R, Heath CH, Kurzai O, Martin R, Litvintseva AP, Cuomo CA. (2020) Tracing the Evolutionary History and Global Expansion of Candida auris Using Population Genomic Analyses. mBio. 11(2). pii: e03364-19. doi: 10.1128/mBio.03364-19.
Plachouras D, Lötsch F, Kohlenberg A, Monnet DL; Candida auris survey collaborative group. (2020) Candida auris: epidemiological situation, laboratory capacity and preparedness in the European Union and European Economic Area*, January 2018 to May 2019. Euro Surveill. 25(12):2000240. doi: 10.2807/1560-7917.ES.2020.25.12.2000240.PMID: 32234118
Marolda A, Hünniger K, Böttcher S, Vivas W, Löffler J, Figge MT, Kurzai O. (2020) Candida species-dependent release of IL-12 by dendritic cells induces different levels of NK cell stimulation. J Infect Dis. pii: jiaa035. doi: 10.1093 / infdis / jiaa035. [Epub ahead of Print]
Zoran T., Weber M., Springer J., White PL, Bauer J., Schober A., Löffler C., Seelbinder B., Hünniger K., Kurzai O., Scherag A., Schäuble S., Morton CO, Einsele H., Linde J., Löffler J. (2019) Treatment with etanercept and low monocyte concentration contribute to the risk of invasive aspergillosis in patients post allogeneic stem cell transplantation. Sci Rep . 2019, 21. November; 9 (1): 17231. doi: 10.1038 / s41598-019-53504-8.
Walther G., Wagner L., Kurzai O. (2019) Updates on the Taxonomy of Mucorales with an Emphasis on Clinically Important Taxa. J Fungi (Basel). 2019 Nov 14;5(4). pii: E106. doi: 10.3390/jof5040106. Review.
Walther G, Wagner L, Kurzai O. (2019) Outbreaks of Mucorales and the Species Involved. Mycopathologia. 2019 Nov 16. doi: 10.1007/s11046-019-00403-1. [Epub ahead of print] Review.
Springer J, Walther G, Rickerts V, Hamprecht A, Willinger B, Teschner D, Einsele H, Kurzai O, Loeffler J. (2019) Detection of Fusarium Species in Clinical Specimens by Probe-Based Real-Time PCR. J Fungi (Basel). 2019 Nov 12;5(4). pii: E105. doi: 10.3390/jof5040105.
Vivas W, Leonhardt I, Hünniger K, Häder A, Marolda A, Kurzai O. (2019) Multiple Signaling Pathways Involved in Human Dendritic Cell Maturation Are Affected by the Fungal Quorum-Sensing Molecule Farnesol. J Immunol. 2019 Dec 1;203(11):2959-2969. doi: 10.4049/jimmunol.1900431. Epub 2019 Oct 16.
Nesseler A, Schauerte N, Geiger C, Kaerger K, Walther G, Kurzai O, Eisenberg T (2019) Sporothrix humicola (Ascomycota: Ophiostomatales) - A soil-borne fungus with pathogenic potential in the eastern quoll (Dasyurus viverrinus). Med Mycol Case Rep. 2019 Jul 30;25:39-44.
Koehler P, Arendrup MC, Arikan-Akdagli S, Bassetti M, Bretagne S, Klingspor L, Lagrou K, Meis JF, Rautemaa-Richardson R, Schelenz S, Hamprecht A, Koehler FC, Kurzai O, Salmanton-García J, Vehreschild JJ, Alanio A, Alastruey-Izquierdo A, Arsic Arsenijevic V, Gangneux JP, Gow NAR, Hadina S, Hamal P, Johnson E, Klimko N, Lass-Flörl C, Mares M, Özenci V, Papp T, Roilides E, Sabino R, Segal E, Talento AF, Tortorano AM, Verweij PE, Hoenigl M, Cornely OA, European Confederation of Medical Mycology (ECMM) (2019) ECMM CandiReg - A ready to use platform for outbreaks and epidemiological studies.. Mycoses. 2019 Oct;62(10):920-927.
Hamprecht A, Barber AE, Mellinghoff SC, Thelen P, Walther G, Yu Y, Neurgaonkar P, Dandekar T, Cornely OA, Martin R, Kurzai O, German Candida auris Study Group (2019) Candida auris in Germany and Previous Exposure to Foreign Healthcare. Emerg Infect Dis. 2019 Sep;25(9):1763-1765.
Wagner L, de Hoog S, Alastruey-Izquierdo A, Voigt K, Kurzai O, Walther G (2019) A Revised Species Concept for Opportunistic Mucor Species Reveals Species-Specific Antifungal Susceptibility Profiles. Antimicrob Agents Chemother. 2019 Jul 25;63(8).
Wagner L, Stielow JB, de Hoog GS, Bensch K, Schwartze VU, Voigt K, Alastruey-Izquierdo A, Kurzai O, Walther G (2019) A new species concept for the clinically relevant Mucor circinelloides complex Persoonia - Molecular Phylogeny and Evolution of Fungi , 67-97.
von Lilienfeld-Toal M, Wagener J, Einsele H, Cornely OA, Kurzai O (2019) Invasive Fungal Infection. Dtsch Arztebl Int. 2019 Apr 19;116(16):271-278.
Al-Zaben N, Medyukhina A, Dietrich S, Marolda A, Hünniger K, Kurzai O, Figge MT (2019) Automated tracking of label-free cells with enhanced recognition of whole tracks. Sci Rep. 2019 Mar 1;9(1):3317.
Roth M, Daas L, Renner-Wilde A, Cvetkova-Fischer N, Saeger M, Herwig-Carl M, Matthaei M, Fekete A, Kakkassery V, Walther G, von Lilienfeld-Toal M, Mertens C, Lenk J, Mehlan J, Fischer C, Fuest M, Kroll S, Bayoudh W, Viestenz A, Frings A, MacKenzie CR, Messmer EM, Seitz B, Kurzai O, Geerling G (2019) [The German keratomycosis registry : Initial results of a multicenter survey]. Ophthalmologe. 2019 Feb 27. doi: 10.1007/s00347-019-0871-9.
Barber AE, Weber M, Kaerger K, Linde J, Gölz H, Duerschmied D, Markert A, Guthke R, Walther G, Kurzai O (2019) Comparative Genomics of Serial Candida glabrata Isolates and the Rapid Acquisition of Echinocandin Resistance during Therapy. Antimicrob Agents Chemother. 2019 Jan 29;63(2).
Voltersen V, Blango MG, Herrmann S, Schmidt F, Heinekamp T, Strassburger M, Krüger T, Bacher P, Lother J, Weiss E, Hünniger K, Liu H, Hortschansky P, Scheffold A, Löffler J, Krappmann S, Nietzsche S, Kurzai O, Einsele H, Kniemeyer O, Filler SG, Reichard U, Brakhage AA (2018) Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus Aspergillus fumigatus. MBio 9(5).
Guinea J, Verweij PE, Meletiadis J, Mouton JW, Barchiesi F, Arendrup MC, Subcommittee on Antifungal Susceptibility Testing (AFST) of the ESCMID European Committee for Antimicrobial Susceptibility Testing (EUCAST, > 20 authors, including Kurzai O. (2018) How to: EUCAST recommendations on the screening procedure E.Def 10.1 for the detection of azole resistance in Aspergillus fumigatus isolates using four well azole-containing agar plates. Clin Microbiol Infect pii: S1198-743X(18)30630-X.
Morton CO, Wurster S, Fliesser M, Ebel F, Page L, Hünniger K, Kurzai O, Schmitt AL, Michel D, Springer J, Einsele H, Loeffler J (2018) Validation of a simplified in vitro Transwell(®) model of the alveolar surface to assess host immunity induced by different morphotypes of Aspergillus fumigatus. Int J Med Microbiol pii: S1438-4221(18)30300-X.
Bloos F, Held J, Schlattmann P, Brillinger N, Kurzai O, Cornely OA, Thomas-Rüddel D (2018) (1,3)-β-D-glucan-based diagnosis of invasive Candida infection versus culture-based diagnosis in patients with sepsis and with an increased risk of invasive Candida infection (CandiSep): study protocol for a randomized controlled trial. Trials 19(1), 472.
Weiss E, Ziegler S, Fliesser M, Schmitt AL, Hünniger K, Kurzai O, Morton CO, Einsele H, Loeffler J (2018) First Insights in NK-DC Cross-Talk and the Importance of Soluble Factors During Infection With Aspergillus fumigatus. Front Cell Infect Microbiol 8, 288.
Leo F, Zeh M, Prothmann A, Kurzai O, Kurz S, Grohé C (2018) Tracheal, laryngeal and pulmonary mucormycosis followed by organizing pneumonia in a patient with Adult Onset Still's Disease. Med Mycol Case Rep 20, 28-32.
Ruhnke M, Behre G, Buchheidt D, Christopeit M, Hamprecht A, Heinz W, Heussel CP, Horger M, Kurzai O, Karthaus M, Löffler J, Maschmeyer G, Penack O, Rieger C, Rickerts V, Ritter J, Schmidt-Hieber M, Schuelper N, Schwartz S, Ullmann A, Vehreschild JJ, von Lilienfeld-Toal M, Weber T, Wolf HH (2018) Diagnosis of invasive fungal diseases in haematology and oncology: 2018 update of the recommendations of the infectious diseases working party of the German society for hematology and medical oncology (AGIHO). Mycoses 61(11), 796-813.
Geißel B, Loiko V, Klugherz I, Zhu Z, Wagener N, Kurzai O, van den Hondel CAMJJ, Wagener J (2018) Azole-induced cell wall carbohydrate patches kill Aspergillus fumigatus. Nat Commun 9(1), 3098.
Timme S, Lehnert T, Prauße MTE, Hünniger K, Leonhardt I, Kurzai O, Figge MT (2018) Quantitative Simulations Predict Treatment Strategies Against Fungal Infections in Virtual Neutropenic Patients. Front Immunol 9, 667.
Prauße MTE, Lehnert T, Timme S, Hünniger K, Leonhardt I, Kurzai O, Figge MT (2018) Predictive Virtual Infection Modeling of Fungal Immune Evasion in Human Whole Blood. Front Immunol 9, 560.
Kohlenberg A, Struelens MJ, Monnet DL, Plachouras D; The Candida Auris Survey Collaborative Group (>40 authors, including Kurzai O. (2018) Candida auris: epidemiological situation, laboratory capacity and preparedness in European Union and European Economic Area countries, 2013 to 2017. Euro Surveill 23(13).
Hünniger K, Kurzai O. (2018) Phagocytes as central players in the defence against invasive fungal infection. Semin Cell Dev Biol pii:S1084-9521(17)30540-2.
Jahreis S, Böttcher S, Hartung S, Rachow T, Rummler S, Dietl AM, Haas H, Walther G, Hochhaus A, von Lilienfeld-Toal M (2018) Human MAIT cells are rapidly activated by Aspergillus spp. in an APC-dependent manner. Eur J Immunol 48(10), 1698-1706.
Brandes S, Dietrich S, Hünniger K, Kurzai O, Figge MT (2017) Migration and Interaction Tracking for Quantitative Analysis of Phagocyte-Pathogen Confrontation Assays. Medical Image Analysis 36, 172-183.
Cunha C, Gonçalves SM, Duarte-Oliveira C, Leite L, Lagrou K, Marques A, Lupiañez CB, Mesquita I, Gaifem J, Barbosa AM, Pinho Vaz C, Branca R, Campilho F, Freitas F, Ligeiro D, Lass-Flörl C, Löffler J, Jurado M, Saraiva M, Kurzai O, Rodrigues F, Castro AG, Silvestre R, Sainz J, Maertens JA, Torrado E, Jacobsen ID, Lacerda JF, Campos A, Carvalho A (2017) IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity. J Allergy Clin Immunol 140(3), 867-870.e9.
Dix A, Czakai K, Leonhardt I, Schäferhoff K, Bonin M, Einsele H, Guthke R, Kurzai O, Löffler J, Linde J (2017) Specific and novel microRNAs are regulated as response to fungal infection in human dendritic cells. Front Microbiol 8, 270
Fischer M, Müller JP, Spies-Weisshart B, Gräfe C, Kurzai O, Hünniger K, Hochhaus A, Scholl S, Schnetzke U (2017) Isoform localization of Dectin-1 regulates the signaling quality of anti-fungal immunity. Eur J Immunol 47(5), 848-859.
Habbe KJ, Frings A, Schrader S, Roth M, MacKenzie C, Walther G, Kurzai O, Geerling G (2017) [Tintelnotia destructans: new enemy at the gates]. Ophthalmologe [Epub ahead of print]
Hsieh SH, Kurzai O, Brock M (2017) Persistence within dendritic cells marks an antifungal evasion and dissemination strategy of Aspergillus terreus. Sci Rep 7(1), 10590.
Martin R, Pohlers S, Mühlschlegel FA, Kurzai O (2017) CO2 sensing in fungi: at the heart of metabolic signaling. Curr Genet 63(6), 965-972.
Pinder N, Pelzl LH, Walther G, Backhaus J, Kurzai O, Hoppe-Tichy T (2017) Caspofungin infusion solutions (50 mg/100 mL): chemical stability and antifungal activity against Candida spp. Pharmazie 72(4), 197-199.
Pohlers S, Martin R, Krüger T, Hellwig D, Hänel F, Kniemeyer O, Saluz HP, Van Dijck, Ernst JF, Brakhage A, Mühlschlegel FA, Kurzai O (2017) Lipid signaling via Pkh1/2 regulates fungal CO2 sensing through the kinase Sch9. mBio 8(1), e02211-16.
Polke M, Leonhardt I, Kurzai O, Jacobsen ID (2017) Farnesol signalling in Candida albicans - more than just communication. Crit Rev Microbiol 44(2), 230-243. (Review)
Polke M, Sprenger M, Scherlach K, Albán-Proaño MC, Martin R, Hertweck C, Hube B, Jacobsen ID (2017) A functional link between hyphal maintenance and quorum sensing in Candida albicans. Mol Microbiol 103(4), 595-617.
Walther G, Stasch S, Kaerger K, Hamprecht A, Roth M, Cornely OA, Geerling G, Mackenzie CR, Kurzai O, von Lilienfeld-Toal M (2017) Fusarium Keratitis in Germany. J Clin Microbiol 55(10), 2983-2995.
Weber M, Schaer J, Walther G, Kaerger K, Steinmann J, Rath PM, Spiess B, Buchheidt D, Hamprecht A, Kurzai O (2017) FunResDB-A web resource for genotypic susceptibility testing of Aspergillus fumigatus. Med Mycol 56(1), 117-120.
Ziegler S, Weiss E, Schmitt AL, Schlegel J, Burgert A, Terpitz U, Sauer M, Moretta L, Sivori S, Leonhardt I, Kurzai O, Einsele H, Loeffler J (2017) CD56 Is a Pathogen Recognition Receptor on Human Natural Killer Cells. Sci Rep 7(1), 6138.
Beitzen-Heineke A, Bouzani M, Schmitt AL, Kurzai O, Hünniger K, Einsele H, Loeffler J (2016) Human Invariant Natural Killer T cells possess immune-modulating functions during Aspergillus infection. Med Mycol 54(2), 169-176.
Blaurock N, Schmerler D, Hünniger K, Kurzai O, Ludewig K, Baier M, Brunkhorst FM, Imhof D, Kiehntopf M (2016) C-Terminal Alpha-1 Antitrypsin Peptide: A New Sepsis Biomarker with Immunomodulatory Function. Mediators Inflamm 2016, 6129437.
Böhringer M, Pohlers S, Schulze S, Albrecht-Eckardt D, Piegsa J, Weber M, Martin R, Hünniger K, Linde J, Guthke R, Kurzai O (2016) Candida albicans infection leads to barrier breakdown and a MAPK/NF-κB mediated stress response in the intestinal epithelial cell line C2BBe1. Cellular Microbiology 18(7), 889-904.
Brandes S, Dietrich S, Hünniger K, Kurzai O, Figge MT (2016) Migration and Interaction Tracking for Quantitative Analysis of Phagocyte-Pathogen Confrontation Assays. Medical Image Analysis 36, 172-183.
Czakai K, Leonhardt I, Dix A, Bonin M, Linde J, Einsele H, Kurzai O, Löffler J (2016) Krüppel-like Factor 4 modulates interleukin-6 release in human dendritic cells after in vitro stimulation with Aspergillus fumigatus and Candida albicans Sci Rep 6, 27990.
Fliesser M, Wallstein M, Kurzai O, Einsele H, Löffler J (2016) Hypoxia attenuates anti-Aspergillus fumigatus immune responses initiated by human dendritic cells. Mycoses 59(8), 503-508.
Hellwig D, Voigt J, Bouzani M, Löffler J, Albrecht-Eckardt D, Weber M, Brunke S, Martin R, Kurzai O, Hünniger K (2016) Candida albicans induces metabolic reprogramming in human NK cells and responds to perforin with a Zinc depletion response. Front Microbiol 7, 750.
Hube B, Kurzai O (2016) Text book chapter in: Clinical Mycology at Oxford University Press. Chapter: Candida. In: Clinical Mycology Oxford University Press.
Janhsen WK, Arnold C, Hentschel J, Lehmann T, Pfister W, Baier M, Böer K, Hünniger K, Kurzai O, Hipler UC, Mainz JG (2016) Colonization of CF patients' upper airways with S. aureus contributes more decisively to upper airway inflammation than P. aeruginosa. Med Microbiol Immunol 205(5), 485-500.
Moyes DL*, Wilson D*, Richardson JP*, Mogavero S*, Tang SX, Wernecke J, Höfs S, Gratacap RL, Robbins J, Runglall M, Murciano C, Blagojevic M, Thavaraj S, Förster TM, Hebecker B, Kasper L, Vizcay G, Iancu SI, Kichik N, Häder A, Kurzai O, Luo T, Krüger T, Kniemeyer O, Cota E, Bader O, Wheeler RT, Gutsmann T, Hube B, Naglik JR (2016) Candidalysin is a fungal peptide toxin critical for mucosal infection. Nature 532(7597), 64-68.
Scherag A, Schöneweck F, Kesselmeier M, Taudien S, Platzer M, Felder M, Sponholz C, Rautanen A, Hill AV, Hinds CJ, Hossain H, Suttorp N, Kurzai O, Slevogt H, Giamarellos-Bourboulis EJ, Armaganidis A, Trips E, Scholz M, Brunkhorst FM (2016) Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28Day Mortality. EBioMedicine 12, 239-246.
Taudien S, Lausser L, Giamarellos-Bourboulis EJ, Sponholz C, Schöneweck F, Felder M, Schirra LR, Schmid F, Gogos C, Groth S, Petersen BS, Franke A, Lieb W, Huse K, Zipfel PF, Kurzai O, Moepps B, Gierschik P, Bauer M, Scherag A, Kestler HA, Platzer M (2016) Genetic Factors of the Disease Course After Sepsis: Rare Deleterious Variants Are Predictive. EBioMedicine 12, 227-238.
Brandes S, Mokhtari Z, Essig F, Hünniger K, Kurzai O, Figge MT (2015) Automated segmentation and tracking of non-rigid objects in time-lapse microscopy videos of polymorphonuclear neutrophils. Medical Image Analysis 20(1), 34-51.
Dix A, Hünniger K, Weber M, Guthke R, Kurzai O, Linde J (2015) Biomarker-based classification of bacterial and fungal whole-blood infections in a genome-wide expression study. Front Microbiol 6, 171.
Duggan S, Essig F, Hünniger K, Mokhtari Z, Bauer L, Lehnert T, Brandes S, Häder A, Jacobsen ID, Martin R, Figge MT, Kurzai O (2015) Neutrophil activation by Candida glabrata but not Candida albicans promotes fungal uptake by monocytes. Cell Microbiol 17(9), 1259-1276.
Duggan S, Leonhardt I, Hünniger K, Kurzai O (2015) Host response to Candida albicans bloodstream infection and sepsis. Virulence, 1-11. (Review)
Essig F, Hünniger K, Dietrich S, Figge MT, Kurzai O (2015) Human neutrophils dump Candida glabrata after intracellular killing. Fungal Genetics and Biology 84, 37-40.
Fliesser M, Morton CO, Bonin M, Ebel F, Hünniger K, Kurzai O, Einsele H, Löffler J (2015) Hypoxia-inducible factor 1α modulates metabolic activity and cytokine release in anti-Aspergillus fumigatus immune responses initiated by human dendritic cells. Int J Med Microbiol 305(8):865-73
Hünniger K, Bieber K, Martin R, Lehnert T, Figge MT, Löffler J, Guo R, Riedemann N, Kurzai O (2015) A second stimulus required for enhanced antifungal activity of human neutrophils in blood is provided by anaphylatoxin C5a. The Journal of Immunology 194(3), 1199-1210.
Huyke J, Martin R, Walther G, Weber M, Kaerger K, Bougnoux ME, Elias J, Kurzai O (2015) Candida albicans bloodstream isolates in a German university hospital are genetically heterogenous and susceptible to commonly used antifungals. Int J Med Microbiol 305(7), 742-747.
Lehnert T*, Timme S*, Pollmächer J, Hünniger K, Kurzai O, Figge MT (2015) Bottom-up modeling approach for the quantitative estimation of parameters in pathogen-host interactions. Frontiers in Microbiology 6(608), *authors contributed equally.
Leonhardt I, Spielberg S, Weber M, Albrecht-Eckardt D, Bläss M, Claus R, Barz D, Scherlach K, Hertweck C, Löffler J, Hünniger K, Kurzai O (2015) The fungal quorum-sensing molecule farnesol activates innate immune cells but suppresses cellular adaptive immunity. MBio 6(2), e00143.
Linde J, Duggan S, Weber M, Horn F, Sieber P, Hellwig D, Riege K, Marz M, Martin R, Guthke R, Kurzai O (2015) Defining the transcriptomic landscape of Candida glabrata by RNA-Seq. Nucleic Acids Res 43(3), 1392-1406.
Cunha C, Aversa F, Lacerda JF, Busca A, Kurzai O, Grube M, Löffler J, Maertens JA, Bell AS, Inforzato A, Barbati E, Almeida B, Santos e Sousa P, Barbui A, Potenza L, Caira M, Rodrigues F, Salvatori G, Pagano L, Luppi M, Mantovani A, Velardi A, Romani L, Carvalho A (2014) Genetic PTX3 deficiency and aspergillosis in stem-cell transplantation. N Engl J Med 370(5), 421-432.
Cunha C, Kurzai O, Carvalho A (2014) PTX3 deficiency and aspergillosis. N Engl J Med 370(17), 1666-1667.
Cunha C, Kurzai O, Löffler J, Aversa F, Romani L, Carvalho A (2014) Neutrophil Responses to Aspergillosis: New Roles for Old Players. Mycopathologia 178(5-6):387-93.
Das Gupta M, Fliesser M, Springer J, Breitschopf T, Schlossnagel H, Schmitt AL, Kurzai O, Hünniger K, Einsele H, Löffler J (2014) Aspergillus fumigatus induces microRNA-132 in human monocytes and dendritic cells. Int J Med Microbiol 304(5-6), 592-596.
Ekaney ML, Otto GP, Sossdorf M, Sponholz C, Boehringer M, Loesche W, Rittirsch D, Wilharm A, Kurzai O, Bauer M, Claus RA (2014) Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation. Crit Care 18(5), 543.
Hentschel J, Müller U, Doht F, Fischer N, Böer K, Sonnemann J, Hipler C, Hünniger K, Kurzai O, Markert UR, Mainz JG (2014) Influences of nasal lavage collection-, processing- and storage methods on inflammatory markers--evaluation of a method for non-invasive sampling of epithelial lining fluid in cystic fibrosis and other respiratory diseases. J Immunol Methods 404, 41-51.
Hünniger K*, Lehnert T*, Bieber K, Martin R, Figge MT⁺, Kurzai O⁺ (2014) A virtual infection model quantifies innate effector mechanisms and Candida albicans immune escape in human blood. PLoS Comput Biol 10(2), e1003479, */⁺authors contributed equally.
Jacobsen ID, Lüttich A, Kurzai O, Hube B, Brock M (2014) In vivo imaging of disseminated murine Candida albicans infection reveals unexpected host sites of fungal persistence during antifungal therapy. J Antimicrob Chemother 69(10), 2785-2796.
Lother J, Breitschopf T, Krappmann S, Morton CO, Bouzani M, Kurzai O, Gunzer M, Hasenberg M, Einsele H, Loeffler J (2014) Human dendritic cell subsets display distinct interactions with the pathogenic mould Aspergillus fumigatus. Int J Med Microbiol 304(8):1160-8.
Miramón P, Dunker C, Kasper L, Jacobsen ID, Barz D, Kurzai O, Hube B (2014) A family of glutathione peroxidases contributes to oxidative stress resistance in Candida albicans. Med Mycol 52(3), 223-239.
Quintin J, Voigt J, van der Voort R, Jacobsen ID, Verschueren I, Hube B, Giamarellos-Bourboulis EJ, van der Meer JW, Joosten LA, Kurzai O, Netea MG (2014) Differential role of NK cells against Candida albicans infection in immunocompetent or immunocompromised mice. Eur J Immunol 44(8), 2405-2414.
Voigt J, Hünniger K, Bouzani M, Jacobsen ID, Barz D, Hube B, Löffler J, Kurzai O (2014) Human natural killer cells acting as phagocytes against Candida albicans and mounting an inflammatory response that modulates neutrophil antifungal activity. J Infect Dis 209(4), 616-626.
Wartenberg A, Linde J, Martin R, Schreiner M, Horn F, Jacobsen ID, Jenull S, Wolf T, Kuchler K, Guthke R, Kurzai O, Forche A, d'Enfert C, Brunke S, Hube B (2014) Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant. PLoS Genet 10(12), e1004824.
Cottier F, Leewattanapasuk W, Kemp LR, Murphy M, Supuran CT, Kurzai O, Mühlschlegel FA (2013) Carbonic anhydrase regulation and CO(2) sensing in the fungal pathogen Candida glabrata involves a novel Rca1p ortholog. Bioorg Med Chem 21(6), 1549-1554.
Luo S, Skerka C, Kurzai O, Zipfel PF (2013) Complement and innate immune evasion strategies of the human pathogenic fungus Candida albicans. Mol Immunol 56(3), 161-169.
Martin R, Albrecht-Eckardt D, Brunke S, Hube B, Hünniger K, Kurzai O (2013) A core filamentation response network in Candida albicans is restricted to eight genes. PLoS One 8(3), e58613.
Palige K, Linde J, Martin R, Böttcher B, Citiulo F, Sullivan DJ, Weber J, Staib C, Rupp S, Hube B, Morschhäuser J, Staib P (2013) Global transcriptome sequencing identifies chlamydospore specific markers in Candida albicans and Candida dubliniensis. PLoS One 8(4), e61940.
Bauer R, Mezger M, Blockhaus C, Schmitt AL, Kurzai O, Einsele H, Loeffler J (2012) 40-O -[2-Hydroxyethyl]rapamycin modulates human dendritic cell function during exposure to Aspergillus fumigatus. J Basic Microbiol 52(3), 269-276.
Cottier F, Raymond M, Kurzai O, Bolstad M, Leewattanapasuk W, Jiménez-López C, Lorenz MC, Sanglard D, Váchová L, Pavelka N, Palková Z, Mühlschlegel FA (2012) The bZIP transcription factor Rca1p is a central regulator of a novel CO₂ sensing pathway in yeast. PLoS Pathog 8(1), e1002485-e1002485.
Escalante-Pérez M, Jaborsky M, Reinders J, Kurzai O, Hedrich R, Ache P (2012) Poplar extrafloral nectar is protected against plant and human pathogenic fungus. Mol Plant 5(5), 1157-1159.
Heddergott C, Bruns S, Nietzsche S, Leonhardt I, Kurzai O, Kniemeyer O, Brakhage AA (2012) The Arthroderma benhamiae hydrophobin HypA mediates hydrophobicity and influences recognition by human immune effector cells. Eukaryot Cell 11(5), 673-682.
Kurzai O, Gow N (2012) A case for case reports-And a new publishing platform for clinical mycology. Med Mycol Case Rep 1(1), 17-18.
Miramón P, Dunker C, Windecker H, Bohovych IM, Brown AJ, Kurzai O, Hube B (2012) Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress. PLoS One 7(12), e52850-e52850.
Bouzani M, Ok M, McCormick A, Ebel F, Kurzai O, Morton CO, Einsele H, Loeffler J (2011) Human NK cells display important antifungal activity against Aspergillus fumigatus, which is directly mediated by IFN-γ release. J Immunol 187(3), 1369-1376.
Hellwig D, Emmerth S, Ulbricht T, Döring V, Hoischen C, Martin R, Samora CP, McAinsh AD, Carroll CW, Straight AF, Meraldi P, Diekmann S (2011) Dynamics of CENP-N kinetochore binding during the cell cycle. J Cell Sci 124(Pt 22), 3871-3883.
Kapp M, Schargus M, Deuchert T, Springer J, Wendel F, Loeffler J, Grigoleit GU, Kurzai O, Heinz W, Einsele H, Stuhler G (2011) Endophthalmitis as primary clinical manifestation of fatal fusariosis in an allogeneic stem cell recipient. Transpl Infect Dis 13(4), 374-379.
Kerstan A, Wendel AM, Kurzai O, Bröcker EB, Kolb-Mäurer A (2011) Ulcerating nodules on the right arm after hunting muskrats. J Dtsch Dermatol Ges 9(6), 487-489.
Martin R, Moran GP, Jacobsen ID, Heyken A, Domey J, Sullivan DJ, Kurzai O, Hube B (2011) The Candida albicans-specific gene EED1 encodes a key regulator of hyphal extension. PLoS One 6(4), e18394.
Martin R, Wächtler B, Schaller M, Wilson D, Hube B (2011) Host-pathogen interactions and virulence-associated genes during Candida albicans oral infections. Int J Med Microbiol 301(5), 417-422. (Review)
Morton CO, Clemons KV, Springer J, Mueller JG, Rogers TR, Stevens DA, Kurzai O, Einsele H, Loeffler J (2011) Real-time PCR and quantitative culture for monitoring of experimental Aspergillus fumigatus intracranial infection in neutropenic mice. J Med Microbiol 60(Pt 7), 913-919.
Morton CO, Varga JJ, Hornbach A, Mezger M, Sennefelder H, Kneitz S, Kurzai O, Krappmann S, Einsele H, Nierman WC, Rogers TR, Loeffler J (2011) The temporal dynamics of differential gene expression in Aspergillus fumigatus interacting with human immature dendritic cells in vitro. PLoS One 6(1), e16016-e16016.
Nägele V, Heesemann J, Schielke S, Jiménez-Soto LF, Kurzai O, Ackermann N (2011) Neisseria meningitidis adhesin NadA targets beta1 integrins: functional similarity to Yersinia invasin. J Biol Chem 286(23), 20536-20546.
Schielke S, Spatz C, Schwarz RF, Joseph B, Schoen C, Schulz SM, Hubert K, Frosch M, Schubert-Unkmeir A, Kurzai O (2011) Characterization of FarR as a highly specialized, growth phase-dependent transcriptional regulator in Neisseria meningitidis. Int J Med Microbiol 301(4), 325-333.
Springer J, Loeffler J, Heinz W, Schlossnagel H, Lehmann M, Morton O, Rogers TR, Schmitt C, Frosch M, Einsele H, Kurzai O (2011) Pathogen-specific DNA enrichment does not increase sensitivity of PCR for diagnosis of invasive aspergillosis in neutropenic patients. J Clin Microbiol 49(4), 1267-1273.
Hornbach A, Heyken A, Schild L, Hube B, Löffler J, Kurzai O (2009) The glycosylphosphatidylinositol-anchored protease Sap9 modulates the interaction of Candida albicans with human neutrophils. Infect Immun 77(12), 5216-5224.
Wilson D, Thewes S, Zakikhany K, Fradin C, Albrecht A, Almeida R, Brunke S, Grosse K, Martin R, Mayer F, Leonhardt I, Schild L, Seider K, Skibbe M, Slesiona S, Waechtler B, Jacobsen I, Hube B (2009) Identifying infection-associated genes of Candida albicans in the postgenomic era. FEMS Yeast Res 9(5), 688-700. (Review)
Wozniok I, Hornbach A, Schmitt C, Frosch M, Einsele H, Hube B, Löffler J, Kurzai O (2008) Induction of ERK-kinase signalling triggers morphotype-specific killing of Candida albicans filaments by human neutrophils. Cell Microbiol 10(3), 807-820.
Zakikhany K, Thewes S, Wilson D, Martin R, Albrecht A, Hube B (2008) From attachment to invasion: infection associated genes of Candida albicans. Nihon Ishinkin Gakkai Zasshi 49(4), 245-251.
Lessing F, Kniemeyer O, Wozniok I, Loeffler J, Kurzai O, Haertl A, Brakhage AA (2007) The Aspergillus fumigatus transcriptional regulator AfYap1 represents the major regulator for defense against reactive oxygen intermediates but is dispensable for pathogenicity in an intranasal mouse infection model. Eukaryot Cell 6(12), 2290-2302.