Klassert TE, Goyal S, Stock M, Driesch D, Hussain A, Berrocal-Almanza LC, Myakala R, Sumanlatha G, Valluri V, Ahmed N, Schumann RR, Flores C, Slevogt H (2018) AmpliSeq Screening of Genes Encoding the C-Type Lectin Receptors and Their Signaling Components Reveals a Common Variant in MASP1 Associated with Pulmonary Tuberculosis in an Indian Population. Front. Immunol., doi: 10.3389/fimmu.2018.00242

Dietert K, Nouailles G, Gutbier B, Reppe K, Berger S, Jiang X, Schauer AE, Hocke AC, Herold S, Slevogt H, Witzenrath M, Suttorp N, Gruber AD (2018) Digital Image Analyses on Whole Lung Slides in Mouse Models of Acute Pneumonia. Am J Respir Cell Mol Biol., doi: 10.1165/rcmb.2017-0337MA. [Epub ahead of print]

Lehmann R, Müller MM, Klassert TE, Driesch D, Stock M, Heinrich A, Conrad T, Moore C, Schier UK, Guthke R, Slevogt H (2018) Differential regulation of the transcriptomic and secretomic landscape of sensor and effector functions of human airway epithelial cells. Mucosal Immunol., doi: 10.1038/mi.2017.100. [Epub ahead of print]


Leonor Fernandes Saraiva JP, Zubiria-Barrera C, Klassert TE, Lautenbach MJ, Blaess M, Claus RA, Slevogt H, König R (2017) Combination of Classifiers Identifies Fungal-Specific Activation of Lysosome Genes in Human Monocytes. Front Microbiol. 8:2366. doi: 10.3389/fmicb.2017.02366. eCollection 2017.

Irmscher S, Döring N, Halder LD, Jo EAH, Kopka I, Dunker C, Jacobsen ID, Luo S, Slevogt H, Lorkowski S, Beyersdorf N, Zipfel PF, Skerka C (2017) Kallikrein Cleaves C3 and Activates Complement. J Innate Immun., doi: 10.1159/000484257. [Epub ahead of print]

Dietert K, Gutbier B, Wienhold SM, Reppe K, Jiang X, Yao L, Chaput C, Naujoks J, Brack M, Kupke A, Peteranderl C, Becker S, von Lachner C, Baal N, Slevogt H, Hocke AC, Witzenrath M, Opitz B, Herold S, Hackstein H, Sander LE, Suttorp N, Gruber AD (2017) Spectrum of pathogen- and model-specific histopathologies in mouse models of acute pneumonia. PLoS One. 12(11):e0188251. doi: 10.1371/journal.pone.0188251. eCollection 2017.

Marx C, Marx-Blümel L, Lindig N, Thierbach R, Hoelzer D, Becker S, Wittig S, Lehmann R, Slevogt H, Heinzel T, Wang ZQ, Beck JF, Sonnemann J (2017) The sirtuin 1/2 inhibitor tenovin-1 induces a nonlinear apoptosis-inducing factor-dependent cell death in a p53 null Ewing's sarcoma cell line. Invest New Drugs, doi: 10.1007/s10637-017-0541-1. [Epub ahead of print]

Saraiva JP, Oswald M, Biering A, Röll D, Assmann C, Klassert T, Blaess M, Czakai K, Claus R, Löffler J, Slevogt H, König R (2017) Fungal biomarker discovery by integration of classifiers. BMC Genomics. 18(1):601. doi: 10.1186/s12864-017-4006-x.

Schauer AE, Klassert TE, von Lachner C, Riebold D, Schneeweiß A, Stock M, Müller MM, Hammerschmidt S, Bufler P, Seifert U, Dietert K, Dinarello CA, Nold MF, Gruber AD, Nold-Petry CA, Slevogt H (2017) IL-37 Causes Excessive Inflammation and Tissue Damage in Murine Pneumococcal Pneumonia. J Innate Immun. 9(4):403-418. doi: 10.1159/000469661.

Müller MM, Lehmann R, Klassert TE, Reifenstein S, Conrad T, Moore C, Kuhn A, Behnert A, Guthke R, Driesch D, Slevogt H (2017) Global analysis of glycoproteins identifies markers of endotoxin tolerant monocytes and GPR84 as a modulator of TNFα expression. Sci Rep. 7: 838.

Klaile E, Müller MM, Schäfer MR, Clauder AK, Feer S, Heyl KA, Stock M, Klassert TE, Zipfel PF, Singer BB, Slevogt H (2017) Binding of Candida albicans to Human CEACAM1 and CEACAM6 Modulates the Inflammatory Response of Intestinal Epithelial Cells. MBio 8(2). pii: e02142-16. doi: 10.1128/mBio.02142-16. 

Huang N, Kny M, Riediger F, Busch K, Schmidt S, Luft FC, Slevogt H, Fielitz J (2017) Deletion of Nlrp3 protects from inflammation-induced skeletal muscle atrophy. Intensive Care Med Exp 5(1):3. doi: 10.1186/s40635-016-0115-0.

Riege K, Hölzer M, Klassert TE, Barth E, Bräuer J, Collatz M, Hufsky F, Mostajo N, Stock M, Vogel B, Slevogt H, Marz M (2017) Massive Effect on LncRNAs in Human Monocytes During Fungal and Bacterial Infections and in Response to Vitamins A and D. Sci Rep 7:40598. doi: 10.1038/srep40598.

Klassert TE, Bräuer J, Hölzer M, Stock M, Riege K, Zubiría-Barrera C, Müller MM, Rummler S, Skerka C, Marz M, Slevogt H (2017) Differential Effects of Vitamins A and D on the Transcriptional Landscape of Human Monocytes during Infection. Sci Rep 7:40599. doi: 10.1038/srep40599.

Tominski D, Katchanov J, Driesch D, Daley MB, Liedtke A, Schneider A, Slevogt H, Arastéh K, Stocker H (2017) The late-presenting HIV-infected patient 30 years after the introduction of HIV testing: spectrum of opportunistic diseases and missed opportunities for early diagnosis. HIV Med 18(2):125-132. doi: 10.1111/hiv.12403.


Goyal S, Klassert TE, Slevogt H (2016) C-type lectin receptors in tuberculosis: what we know. Med Microbiol Immunol 205(6):513-535. Review.

Scherag A, Schöneweck F, Kesselmeier M, Taudien S, Platzer M, Felder M, Sponholz C, Rautanen A, Hill AV, Hinds CJ, Hossain H, Suttorp N, Kurzai O, Slevogt H, Giamarellos-Bourboulis EJ, Armaganidis A, Trips E, Scholz M, Brunkhorst FM (2016) Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28Day Mortality. EBioMedicine 12:239-246. doi: 10.1016/j.ebiom.2016.08.043.

Heinrich A, Heyl KA, Klaile E, Müller MM, Klassert TE, Wiessner A, Fischer K, Schumann RR, Seifert U, Riesbeck K, Moter A, Singer BB, Bachmann S, Slevogt H (2016) Moraxella catarrhalis induces CEACAM3-Syk-CARD9-dependent activation of human granulocytes. Cell Microbiol 18(11):1570-1582. doi: 10.1111/cmi.12597.

Javaheri A, Kruse T, Moonens K, Mejías-Luque R, Debraekeleer A, Asche CI, Tegtmeyer N, Kalali B, Bach NC, Sieber SA, Hill DJ, Königer V, Hauck CR, Moskalenko R, Haas R, Busch DH, Klaile E, Slevogt H, Schmidt A, Backert S, Remaut H, Singer BB, Gerhard M (2016) Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs. Nat Microbiol. 2:16189. doi: 10.1038/nmicrobiol.2016.189. Erratum: Nat Microbiol 2016 Nov 7;2:16243. doi: 10.1038/nmicrobiol.2016.243. 

Heyl KA, Karsten CM, Slevogt H (2016) Galectin-3 binds highly galactosylated IgG1 and is crucial for the IgG1 complex mediated inhibition of C5aReceptor induced immune responses. Biochem Biophys Res Commun 479(1):86-90. doi: 10.1016/j.bbrc.2016.09.038.

Berrocal-Almanza LC, Goyal S, Hussain A, Klassert TE, Driesch D, Grozdanovic Z, Sumanlatha G, Ahmed N, Valluri V, Conrad ML, Dittrich N, Schumann RR, Lala B, Slevogt H (2016) S100A12 is up-regulated in pulmonary tuberculosis and predicts the extent of alveolar infiltration on chest radiography: an observational study. Sci Rep 6:31798. doi: 10.1038/srep31798.

Manchanda H, Seidel N, Blaess MF, Claus RA, Linde J, Slevogt H, Sauerbrei A, Guthke R, Schmidtke M (2016) Differential Biphasic Transcriptional Host Response Associated with Coevolution of Hemagglutinin Quasispecies of Influenza A Virus. Front Microbiol 7:1167. doi: 10.3389/fmicb.2016.01167.

Heinrich A, Haarmann H, Zahradnik S, Frenzel K, Schreiber F, Klassert TE, Heyl KA, Endres AS, Schmidtke M, Hofmann J, Slevogt H (2016) Moraxella catarrhalis decreases antiviral innate immune responses by down-regulation of TLR3 via inhibition of p53 in human bronchial epithelial cells. FASEB J 30(6):2426-34. doi: 10.1096/fj.201500172R.

Katchanov J, Wöstmann K, Tominski D, Jefferys L, Liedtke A, Schneider A, Slevogt H, Arastéh K, Stocker H (2016) Burden and spectrum of infectious disease in Germany 2009-2014: a multicentre study from Berlin's Municipal Hospitals. Infection 44(2):187-95. doi: 10.1007/s15010-015-0834-2.


Haarmann H, Steiner T, Schreiber F, Heinrich A, Zweigner J, N'Guessan PD, Slevogt H (2015) The role and regulation of Moraxella catarrhalis-induced human beta-defensin 3 expression in human pulmonary epithelial cells. Biochem Biophys Res Commun 467(1):46-52. doi: 10.1016/j.bbrc.2015.09.126.

Grozdanovic Z, Berrocal Almanza LC, Goyal S, Hussain A, Klassert TE, Driesch D, Tokaryeva V, Löschmann YY, Sumanlatha G, Ahmed N, Valluri V, Schumann RR, Lala B, Slevogt H (2015) A Novel Reading Scheme for Assessing the Extent of Radiographic Abnormalities and Its Association with Disease Severity in Sputum Smear-Positive Tuberculosis: An Observational Study in Hyderabad/India. PLoS One 10(9):e0138070. doi: 10.1371/journal.pone.0138070.

Acosta-Herrera M, Lorenzo-Diaz F, Pino-Yanes M, Corrales A, Valladares F, Klassert TE, Valladares B, Slevogt H, Ma SF, Villar J, Flores C (2015) Lung Transcriptomics during Protective Ventilatory Support in Sepsis-Induced Acute Lung Injury. PLoS One. 10(7):e0132296. doi: 10.1371/journal.pone.0132296. Erratum in: PLoS One 10(12):e0145696.

Gutbier B, Fischer K, Doehn JM, von Lachner C, Herr C, Klaile E, Frischmann U, Singer BB, Riesbeck K, Zimmermann W, Suttorp N, Bachmann S, Bals R, Witzenrath M, Slevogt H (2015) Moraxella catarrhalis induces an immune response in the murine lung that is independent of human CEACAM5 expression and long-term smoke exposure. Am J Physiol Lung Cell Mol Physiol 309(3):L250-61. doi: 10.1152/ajplung.00265.2014.

Dittrich N, Berrocal-Almanza LC, Thada S, Goyal S, Slevogt H, Sumanlatha G, Hussain A, Sur S, Burkert S, Oh DY, Valluri V, Schumann RR, Conrad ML (2015) Toll-like receptor 1 variations influence susceptibility and immune response to Mycobacterium tuberculosis. Tuberculosis (Edinb) 95(3):328-35. doi: 10.1016/

Katchanov J, Jefferys L, Tominski D, Wöstmann K, Slevogt H, Arastéh K, Stocker H (2015) Cryptococcosis in HIV-infected hospitalized patients in Germany: Evidence for routine antigen testing. J Infect 71(1):110-6. doi: 10.1016/j.jinf.2015.01.011.

Walther E, Richter M, Xu Z, Kramer C, von Grafenstein S, Kirchmair J, Grienke U, Rollinger JM, Liedl KR, Slevogt H, Sauerbrei A, Saluz HP, Pfister W, Schmidtke M (2015) Antipneumococcal activity of neuraminidase inhibiting artocarpin. Int J Med Microbiol 305(3):289-97. doi: 10.1016/j.ijmm.2014.12.004.


Heyl KA, Klassert TE, Heinrich A, Müller MM, Klaile E, Dienemann H, Grünewald C, Bals R, Singer BB, Slevogt H (2014) Dectin-1 is expressed in human lung and mediates the proinflammatory immune response to nontypeable Haemophilus influenzae. MBio 5(5):e01492-14. doi: 10.1128/mBio.01492-14.

Klassert TE, Hanisch A, Bräuer J, Klaile E, Heyl KA, Mansour MK, Tam JM, Vyas JM, Slevogt H (2014) Modulatory role of vitamin A on the Candida albicans-induced immune response in human monocytes. Med Microbiol Immunol 203(6):415-24. doi: 10.1007/s00430-014-0351-4. Erratum: Med Microbiol Immunol 203(6):425. Mansour, Michael M [corrected to Mansour, Michael K]. 

N'Guessan PD, Haarmann H, Steiner T, Heyl K, Schreiber F, Heinrich A, Slevogt H (2014) The Moraxella catarrhalis-induced pro-inflammatory immune response is enhanced by the activation of the epidermal growth factor receptor in human pulmonary epithelial cells. Biochem Biophys Res Commun 450(2):1038-44. doi: 0.1016/j.bbrc.2014.06.102.

Singer BB, Opp L, Heinrich A, Schreiber F, Binding-Liermann R, Berrocal-Almanza LC, Heyl KA, Müller MM, Weimann A, Zweigner J, Slevogt H (2014) Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses. PLoS One 17;9(4):e94106. doi: 10.1371/journal.pone.0094106.


Klaile E, Klassert TE, Scheffrahn I, Müller MM, Heinrich A, Heyl KA, Dienemann H, Grünewald C, Bals R, Singer BB, Slevogt H (2013) Carcinoembryonic antigen (CEA)-related cell adhesion molecules are co-expressed in the human lung and their expression can be modulated in bronchial epithelial cells by non-typable Haemophilus influenzae, Moraxella catarrhalis, TLR3, and type I and II interferons. Respir Res 14:85. doi: 10.1186/1465-9921-14-85.

Weimann A, Rieger A, Zimmermann M, Gross M, Hoffmann P, Slevogt H, Morawietz L (2010) Comparison of six immunohistochemical markers for the histologic diagnosis of neoplasia in Barrett's esophagus. Virchows Arch. 457(5):537-45. doi: 10.1007/s00428-010-0972-y .

Weimann A, Zimmermann M, Gross M, Slevogt H, Rieger A, Morawietz L (2010) CDX2 and LI-cadherin expression in esophageal mucosa: use of both markers can facilitate the histologic diagnosis of Barrett's esophagus and carcinoma. Int J Surg Pathol. 18(5):330-7. doi: 10.1177/1066896910364228 .

Singer BB, Scheffrahn I, Kammerer R, Suttorp N, Ergun S, Slevogt H (2010) Deregulation of the CEACAM expression pattern causes undifferentiated cell growth in human lung adenocarcinoma cells. PLoS One. 5(1):e8747. doi: 10.1371/journal.pone.0008747.

Meixenberger K, Pache F, Eitel J, Schmeck B, Hippenstiel S, Slevogt H, N'Guessan P, Witzenrath M, Netea MG, Chakraborty T, Suttorp N, Opitz B (2010) Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3. J Immunol. 184(2):922-30. doi: 10.4049/jimmunol.0901346.

Vardarova K, Scharf S, Lang F, Schmeck B, Opitz B, Eitel J, Hocke AC, Slevogt H, Flieger A, Hippenstiel S, Suttorp N, N'guessan PD (2009) PKC(alpha) and PKC(epsilon) differentially regulate Legionella pneumophila-induced GM-CSF. Eur Respir J. 34(5):1171-9. doi: 10.1183/09031936.00171908 .

Dje N'Guessan P, Riediger F, Vardarova K, Scharf S, Eitel J, Opitz B, Slevogt H, Weichert W, Hocke AC, Schmeck B, Suttorp N, Hippenstiel S (2009). Statins control oxidized LDL-mediated histone modifications and gene expression in cultured human endothelial cells. Arterioscler Thromb Vasc Biol. 29(3):380-6. doi: 10.1161/ATVBAHA.108.178319.

Slevogt H, Zabel S, Opitz B, Hocke A, Eitel J, N'guessan PD, Lucka L, Riesbeck K, Zimmermann W, Zweigner J, Temmesfeld-Wollbrueck B, Suttorp N, Singer BB (2008) CEACAM1 inhibits Toll-like receptor 2-triggered antibacterial responses of human pulmonary epithelial cells. Nat Immunol. 9(11):1270-8. doi: 10.1038/ni.1661.

Lippmann J, Rothenburg S, Deigendesch N, Eitel J, Meixenberger K, van Laak V, Slevogt H, N'guessan PD, Hippenstiel S, Chakraborty T, Flieger A, Suttorp N, Opitz B (2008) IFNbeta responses induced by intracellular bacteria or cytosolic DNA in different human cells do not require ZBP1 (DLM-1/DAI). Cell Microbiol. 10(12):2579-88. doi: 10.1111/j.1462-5822.2008.01232.x.

Eitel J, Krüll M, Hocke AC, N'Guessan PD, Zahlten J, Schmeck B, Slevogt H, Hippenstiel S, Suttorp N, Opitz B (2008) Beta-PIX and Rac1 GTPase mediate trafficking and negative regulation of NOD2. J Immunol. 181(4):2664-71.

Schmeck B, Lorenz J, N'guessan PD, Opitz B, van Laak V, Zahlten J, Slevogt H, Witzenrath M, Flieger A, Suttorp N, Hippenstiel S (2008) Histone acetylation and flagellin are essential for Legionella pneumophila-induced cytokine Expression. J Immunol. 181(2):940-7.

Vinzing M, Eitel J, Lippmann J, Hocke AC, Zahlten J, Slevogt H, N'guessan PD, Günther S, Schmeck B, Hippenstiel S, Flieger A, Suttorp N, Opitz B (2008) NAIP and Ipaf control Legionella pneumophila replication in human cells. J Immunol. 180(10):6808-15.

Slevogt H, Maqami L, Vardarowa K, Beermann W, Hocke AC, Eitel J, Schmeck B, Weimann A, Opitz B, Hippenstiel S, Suttorp N, N'Guessan PD (2008) Differential regulation of Moraxella catarrhalis-induced interleukin-8 response by protein kinase C isoforms. Eur Respir J. 31(4):725-35. doi: 10.1183/09031936.00103507.

N'Guessan PD, Temmesfeld-Wollbrück B, Zahlten J, Eitel J, Zabel S, Schmeck B, Opitz B, Hippenstiel S, Suttorp N, Slevogt H (2007) Moraxella catarrhalis induces ERK- and NF-kappaB-dependent COX-2 and prostaglandin E2 in lung Epithelium. Eur Respir J. 30(3):443-51.

N'Guessan PD, Vigelahn M, Bachmann S, Zabel S, Opitz B, Schmeck B, Hippenstiel S, Zweigner J, Riesbeck K, Singer BB, Suttorp N, Slevogt H (2007) The UspA1 protein of Moraxella catarrhalis induces CEACAM-1-dependent apoptosis in alveolar epithelial cells. J Infect Dis. 195(11):1651-60.

Slevogt H, Seybold J, Tiwari KN, Hocke AC, Jonatat C, Dietel S, Hippenstiel S, Singer BB, Bachmann S, Suttorp N, Opitz B (2007) Moraxella catarrhalis is internalized in respiratory epithelial cells by a trigger-like mechanism and initiates a TLR2- and partly NOD1-dependent inflammatory immune Response. Cell Microbiol. 9(3):694-707.

Opitz B, Vinzing M, van Laak V, Schmeck B, Heine G, Günther S, Preissner R, Slevogt H, N'Guessan PD, Eitel J, Goldmann T, Flieger A, Suttorp N, Hippenstiel S (2006) Legionella pneumophila induces IFNbeta in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication. J Biol Chem. 281(47):36173-9.

Slevogt H, Schmeck B, Jonatat C, Zahlten J, Beermann W, van Laak V, Opitz B, Dietel S, N'Guessan PD, Hippenstiel S, Suttorp N, Seybold J (2006) Moraxella catarrhalis induces inflammatory response of bronchial epithelial cells via MAPK and NF-kappaB activation and histone deacetylase activity reduction. Am J Physiol Lung Cell Mol Physiol. 290(5):L818-26.

Slevogt H, Tiwari KN, Schmeck B, Hocke A, Opitz B, Suttorp N, Seybold J (2006) Adhesion of Moraxella catarrhalis to human bronchial epithelium characterized by a novel fluorescence-based Assay. Med Microbiol Immunol. 95(2):73-83

Rosseau S, Wiechmann K, Moderer S, Selhorst J, Mayer K, Krüll M, Hocke A, Slevogt H, Seeger W, Suttorp N, Seybold J, Lohmeyer J (2005) Moraxella catarrhalis--infected alveolar epithelium induced monocyte recruitment and oxidative burst. Am J Respir Cell Mol Biol. 32(2):157-66.

Slevogt H, Tintelnot K, Seybold J, Suttorp N (2004) Lymphadenopathy in a pregnant woman from Brazil. Lancet. 363(9417):1282.

Höflich C, Sabat R, Rosseau S, Temmesfeld B, Slevogt H, Döcke WD, Grütz G, Meisel C, Halle E, Göbel UB, Volk HD, Suttorp N (2004) Naturally occurring anti-IFN-gamma autoantibody and severe infections with Mycobacterium cheloneae and Burkholderia cocovenenans. Blood 103(2):673-5 .

Slevogt H, Grobusch MP, Suttorp N (2003) Gnathostomiasis without eosinophilia led to a 5-year delay in diagnosis. J Travel Med. 10(3):196 .

Grobusch MP, Bollmann R, Schönberg A, Slevogt H, Garcia V, Teichmann D, Jelinek T, Flick H, Bergmann F, Rosseau S, Temmesfeld-Wollbrück B, Suttorp N (2003) Leptospirosis in travelers returning from the Dominican Republic. J Travel Med. 10(1):55-8 .

Slevogt H, Schiller R, Wesselmann H, Suttorp N (2001) Ascending cellulitis after an insect bite. Lancet 357(9258):768.