Publikationen
Saugel B, Meidert AS, Brunkhorst FM, et al., > 20 authors, including Coldewey SM (2025) Individualized Perioperative Blood Pressure Management in Patients Undergoing Major Abdominal Surgery: The IMPROVE-multi Randomized Clinical Trial. JAMA . 2025 Oct 12:e2517235. doi: 10.1001/jama.2025.17235. Online ahead of print. PMID: 41076588. Publication
Standke A, Neu C, Baumbach P, Plooij AK, Skitek K, Götze J, Coldewey SM (2025) Reversible impairment of non-invasively assessed mitochondrial oxygen metabolism in the long-term course of patients with sepsis: a prospective monocentric cohort study. Intensive Care Med Exp. 2025 Nov 14;13(1):114. doi: 10.1186/s40635-025-00808-x. PMID: 41233688. Publication
Ramoji A, Baumbach P, Ryabchykov O, Pistiki A, Rueger J, Pinzon DV, Silge A, Deinhardt-Emmer S, Schie IW, Weber K, Neu C, Neugebauer U, Kiehntopf M, Bocklitz T, Popp J, Coldewey SM (2025) Raman Spectroscopy Can Identify Acute and Persistent Biochemical Changes in Leukocytes From Patients With COVID-19 and Non-COVID-19-Associated Sepsis. Biotechnol J. 2025 Sep;20(9):e70105. doi: 10.1002/biot.70105. PMID: 40891106. Publication
Krieg N, Baumbach P, Ceanga IA, Standke A, Gräler MH, Claus RA, Nicklas JY, Winkler MS, Saugel B, Coldewey SM (2025) Prognostic value of perioperative changes in serum primary metabolites in patients after major surgery under general anesthesia: an exploratory secondary analysis of the TAPIR trial. Can J Anaesth. 2025 Jun;72(6):954-965. doi: 10.1007/s12630-025-02984-6. PMID: 40586833. Publication
Engelmann M, Götze J, Baumbach P, Neu C, Settmacher U, Ardelt M, Kissler H, Coldewey SM (2025) Mitochondrial oxygen metabolism as a potential predictor of weight loss after laparoscopic sleeve gastrectomy for class III obesity. Front Endocrinol (Lausanne). 2025 Jan 7:15:1488175. doi: 10.3389/fendo.2024.1488175. eCollection 2024. PMID: 39839477. Publication
Mandal S, Motganhalli Ravikumar R, Tannert A, Urbanek A, Guliev RR, Naumann M, Coldewey SM, Dahmen U, Carvalho L, Bastião Silva L, Neugebauer U (2025) Qualitative comparison of decalcifiers for mouse bone cryosections for subsequent biophotonic analysis. Sci Rep. 2025 Jan 7;15(1):1153. doi: 10.1038/s41598-024-84330-2. PMID: 39774725. Publication
Mestekemper AN, Pirschel W, Krieg N, Paulmann MK, Daniel C, Amann K, Coldewey SM (2024) Reduction in Renal Heme Oxygenase-1 Is Associated with an Aggravation of Kidney Injury in Shiga Toxin-Induced Murine Hemolytic-Uremic Syndrome. Toxins (Basel). 2024 Dec 14;16(12):543. doi: 10.3390/toxins16120543. PMID: 39728801. Publication
Verra C, Paulmann MK, Wegener J, Marzani E, Ferreira Alves G, Collino M, Coldewey SM, Thiemermann C (2024) Spleen tyrosine kinase: a novel pharmacological target for sepsis-induced cardiac dysfunction and multi-organ failure. Front Immunol. 2024 Nov 4;15:1447901. doi: 10.3389/fimmu.2024.1447901. eCollection 2024. PMID: 39559354. Publication
Wegener J, Dennhardt S, Löffler I, Coldewey SM (2024) Transition from acute kidney injury to chronic kidney disease in a long-term murine model of Shiga toxin-induced hemolytic-uremic syndrome. Front Immunol. 2024 Oct 10;15:1469353. doi: 10.3389/fimmu.2024.1469353. eCollection 2024. PMID: 39450175. Publication
Kröller S, Schober J, Krieg N, Dennhardt S, Pirschel W, Kiehntopf M, Conway EM, Coldewey SM (2024) The Role of the N-Terminal Domain of Thrombomodulin and the Potential of Recombinant Human Thrombomodulin as a Therapeutic Intervention for Shiga Toxin-Induced Hemolytic-Uremic Syndrome. Toxins (Basel). 2024 Sep 20;16(9):409. doi: 10.3390/toxins16090409. PMID: 39330867. Publication
Schaller SJ, Scheffenbichler FT, Bein T, Blobner M, Grunow JJ, Hamsen U, Hermes C, Kaltwasser A, Lewald H, Nydahl P, Reißhauer A, Renzewitz L, Siemon K, Staudinger T, Ullrich R, Weber-Carstens S, Wrigge H, Zergiebel D, Coldewey SM (2024) Guideline on positioning and early mobilisation in the critically ill by an expert panel. Intensive Care Med. 2024 Aug;50(8):1211-1227. doi: 10.1007/s00134-024-07532-2. Epub 2024 Jul 29. PMID: 39073582. Publication
Müller T, Krieg N, Lange-Polovinkin AI, Wissuwa B, Gräler MH, Dennhardt S, Coldewey SM (2024) Deletion of Sphingosine Kinase 2 Attenuates Acute Kidney Injury in Mice with Hemolytic-Uremic Syndrome. Int J Mol Sci. 2024 Jul 12;25(14):7683. doi: 10.3390/ijms25147683. PMID: 39062926. Publication
Relja B, Ghezzi P, Coldewey SM, Pavlov VA, Bhatia M, Jungwirth B, Thiemermann C (2024) Editorial: Community series in translational insights into mechanisms and therapy of organ dysfunction in sepsis and trauma - volume III. Front Immunol. 2024 Jul 11;15:1447892. doi: 10.3389/fimmu.2024.1447892. eCollection 2024. PMID: 39055705. Publication
Dennhardt S, Ceanga IA, Baumbach P, Amiratashani M, Kröller S, Coldewey SM (2024) Cell-free DNA in patients with sepsis: long term trajectory and association with 28-day mortality and sepsis-associated acute kidney injury. Front Immunol. 2024 May 13;15:1382003. doi: 10.3389/fimmu.2024.1382003. eCollection 2024. PMID: 38803503. Publication
Teichgräber U, Ingwersen M, Sturm MJ, Giesecke J, Allwang M, Herzog I, von Gierke F, Schellong P, Kolleg M, Lange K, Wünsch D, Gugel K, Wünsch A, Zöllkau J, Petruschke I, Häseler-Ouart K, Besteher B, Philipp S, Mille U, Ouart D, Jünger J; Jena Planetary Health Collaboration Group, > 20 authors, including Coldewey SM (2024) Objective structured clinical examination to teach competency in planetary health care and management - a prospective observational study. BMC Med Educ. 2024 Mar 19;24(1):308. doi: 10.1186/s12909-024-05274-9. PMID: 38504289. Publication
Neu C, Esper Treml R, Baumbach P, Engelmann M, Gebhardt C, Götze J, Coldewey SM (2024) Cholinesterase activities and sepsis-associated encephalopathy in viral versus nonviral sepsis. Can J Anaesth. 2024 Mar;71(3):378-389. doi: 10.1007/s12630-024-02692-7. Epub 2024 Mar 1. PMID: 38429621. Publication
Türk EE, Coldewey SM (2023) Rechtsmedizinische Aspekte der perioperativen Versorgung von Gewaltopfern – Schritt für Schritt (2023) Intensivmedizin up2date 2023; 19(04): 381-386. doi: 10.1055/a-2151-7869. Publication
Hülsmann J, Lindemann H, Wegener J, Kühne M, Godmann M, Koschella A, Coldewey SM, Heinze T, Heinzel T (2023) Dually Modified Cellulose as a Non-Viral Vector for the Delivery and Uptake of HDAC3 siRNA. Pharmaceutics. 2023 Nov 23;15(12):2659. doi: 10.3390/pharmaceutics15122659. PMID: 38140000. Publication
Neu C, Wissuwa B, Thiemermann C, Coldewey SM (2023) Cardiovascular impairment in Shiga-toxin-2-induced experimental hemolytic-uremic syndrome: a pilot study. Front Immunol. 2023 Sep 22;14:1252818. doi: 10.3389/fimmu.2023.1252818. eCollection 2023. PMID: 37809105. Publication
Coldewey SM, Neu C, Sekhar K, Gebhardt C (2023) Septische Kardiomyopathie – Pathophysiologie, Diagnostik und Therapie. DIVI 2023; 14:196-204, doi: 10.53180/DIVI.2023.0196-0204
Patel NM, Collotta D, Aimaretti E, Ferreira Alves G, Kröller S, Coldewey SM, Collino M, Thiemermann C (2023) Inhibition of the JAK/STAT Pathway With Baricitinib Reduces the Multiple Organ Dysfunction Caused by Hemorrhagic Shock in Rats. Ann Surg. 2023 Jul 1;278(1):e137-e146. doi: 10.1097/SLA.0000000000005571. Epub 2022 Jul 15. PMID: 35837955. Publication
Relja B, Coldewey SM, Ghezzi P, Martin L, Thiemermann C (2023) Editorial: Community series in translational insights into mechanisms and therapy of organ dysfunction in sepsis and trauma, volume II. Front Immunol. 2023 May 25;14:1215888. doi: 10.3389/fimmu.2023.1215888. eCollection 2023. PMID: 37304276. Publication
Mandal S, Tannert A, Ebert C, Guliev RR, Ozegowski Y, Carvalho L, Wildemann B, Eiserloh S, Coldewey SM, Löffler B, Bastião Silva L, Hoerr V, Tuchscherr L, Neugebauer U (2023) Insights into S. aureus-Induced Bone Deformation in a Mouse Model of Chronic Osteomyelitis Using Fluorescence and Raman Imaging. Int J Mol Sci. 2023 Jun 5;24(11):9762. doi: 10.3390/ijms24119762. PMID: 37298718. Publication
Chung HY, Wickel J, Hahn N, Mein N, Schwarzbrunn M, Koch P, Ceanga M, Haselmann H, Baade-Büttner C, von Stackelberg N, Hempel N, Schmidl L, Groth M, Andreas N, Götze J, Coldewey SM, Bauer M, Mawrin C, Dargvainiene J, Leypoldt F, Steinke S, Wang ZQ, Hust M, Geis C. (2023) Microglia mediate neurocognitive deficits by eliminating C1q-tagged synapses in sepsis-associated encephalopathy. Sci Adv. 2023 May 26;9(21):eabq7806. doi: 10.1126/sciadv.abq7806. Epub 2023 May 26. PMID: 37235660. Publication
Patel NM, Oliveira FRMB, Ramos HP, Aimaretti E, Alves GF, Coldewey SM, Collino M, Sordi R, Thiemermann C (2023) Inhibition of Bruton's Tyrosine Kinase Activity Attenuates Hemorrhagic Shock-Induced Multiple Organ Dysfunction in Rats. Ann Surg. 2023 Mar 1;277(3):e624-e633. doi: 10.1097/SLA.0000000000005357. Epub 2021 Dec 27. PMID: 35129479. Publication
Kröller S, Wissuwa B, Dennhardt S, Krieg N, Thiemermann C, Daniel C, Amann K, Gunzer F, Coldewey SM (2023) Bruton's tyrosine kinase inhibition attenuates disease progression by reducing renal immune cell invasion in mice with hemolytic-uremic syndrome. Front Immunol. 2023 Feb 23;14:1105181. doi: 10.3389/fimmu.2023.1105181. eCollection 2023. PMID: 36911665. Publication
Bigge R, Bunk B, Rudolph WW, Gunzer F, Coldewey SM, Riedel T, Schröttner P (2022) Comparative Study of Different Diagnostic Routine Methods for the Identification of Acinetobacter radioresistens. Microorganisms. 2022 Aug 31;10(9):1767. doi:10.3390/microorganisms10091767. PMID: 36144369. Publication
Dennhardt S, Pirschel W, Wissuwa B, Imhof D, Daniel C, Kielstein JT, Hennig-Pauka I, Amann K, Gunzer F, Coldewey SM (2022) Targeting the Innate Repair Receptor Axis via Erythropoietin or Pyroglutamate Helix B Surface Peptide attenuates Hemolytic-Uremic Syndrome in Mice. Front Immunol. 2022 Sep 23;13:1010882. doi: 10.3389/fimmu.2022.1010882. eCollection 2022. PMID: 36211426. Publication
Coldewey SM, Neu C, Bloos F, Baumbach P, Schumacher U, Bauer M, Reuken P, Stallmach A (2022) Infliximab in the treatment of patients with severe COVID-19 (INFLIXCOVID): protocol for a randomised, controlled, multicentre, open label phase II clinical study. Trials. 2022 Sep 2;23(1):737. doi: 10.1186/s13063-022-06566-5. PMID: 36056419. Publication
Kopf A, Bunk B, Coldewey SM, Gunzer F, Riedel T, Schröttner P (2022) Comparative Genomic Analysis of the Human Pathogen Wohlfahrtiimonas Chitiniclastica Provides Insight Into the Identification of Antimicrobial Resistance Genotypes and Potential Virulence Traits. Front Cell Infect Microbiol. 2022 Jul 7;12:912427. doi: 10.3389/fcimb.2022.912427. eCollection 2022. PMID: 35873140. Publication
Herminghaus A, Kozlov AV, Szabó A, Hantos Z, Gylstorff S, Kuebart A, Aghapour M, Wissuwa B, Walles T, Walles H, Coldewey SM, Relja B (2022) A barrier to defend - Models of pulmonary barrier to study acute inflammatory diseases, Front Immunol. 2022 Jul 7;13:895100. doi: 10.3389/fimmu.2022.895100. eCollection 2022. PMID: 35874776. Publication
Neu C, Baumbach P, Scherag A, Kortgen A, Götze J, Coldewey SM (2022) Identification of cardiovascular and molecular prognostic factors for the morbidity and mortality in COVID-19-sepsis (ICROVID): protocol for a prospective multi-centre cohort study. PLoS One. 2022 Jun 3;17(6):e0269247. doi: 10.1371/journal.pone.0269247. eCollection 2022. PMID: 35658058. Publication
Neu C, Skitek K, Kissler H, Baumbach P, Settmacher U, Esper Treml R, Coldewey SM (2022) Body composition, mitochondrial oxygen metabolism and metabolome of patients with obesity before and after bariatric surgery (COMMITMENT): protocol for a monocentric prospective cohort study. BMJ Open. 2022 Jun 3;12(6):e062592. doi: 10.1136/bmjopen-2022-062592. PMID: 35925679. Publication
Bigalke A, Neu C, Esper Treml R, Coldewey SM, Kiehntopf M (2022) Fragments of alpha-1-antitrypsin in patients with severe COVID-19 and bacterial pulmonary sepsis. Clin Chem Lab Med. 2022 May 4;60(8):e187-e189. doi: 10.1515/cclm-2022-0361. Print 2022 Jul 26. PMID: 35503554. Publication
Pirschel W, Mestekemper AN, Wissuwa B, Krieg N, Kröller S, Daniel C, Gunzer F, Tolosano E, Bauer M, Amann K, Heinemann SH, Coldewey SM (2022) Divergent roles of haptoglobin and hemopexin deficiency for disease progression of Shiga-toxin-induced hemolytic-uremic syndrome in mice. Kidney Int. 2022 Jun;101(6):1171-1185. doi: 10.1016/j.kint.2021.12.024. Epub 2022 Jan 11. PMID: 35031328. Publication
Metzing UB, von Loeffelholz C, Steidl R, Romeike B, Winkler R, Rauchfuß F, Settmacher U, Stoppe C, Coldewey SM, Weinmann C, Weickert MO, Claus RA, Birkenfeld AL, Kosan C, Horn P (2022) Endoplasmic reticulum stress and the unfolded protein response in skeletal muscle of subjects suffering from peritoneal Sepsis. Sci Rep. 2022 Jan 11;12(1):504. doi: 10.1038/s41598-021-04517-9. PMID: 35017615. Publication
von Loeffelholz C, Roth J, Coldewey SM, Birkenfeld AL (2021) The Role of Physical Activity in Nonalcoholic and Metabolic Dysfunction Associated Fatty Liver Disease. Biomedicines. 2021 Dec 7;9(12):1853. doi: 10.3390/biomedicines9121853. PMID: 34944668. Publication
Winkler MS, Claus RA, Schilder M, Pöhlmann S, Coldewey SM, Grundmann J, Fricke T, Moerer O, Meissner K, Bauer M, Hofmann-Winkler H, Gräler M (2021) Erythrocytes increase endogenous sphingosine 1-phosphate levels as an adaptive response to SARS-CoV-2 infection. Clin Sci (Lond). 2021 Dec 22;135(24):2781-2791. doi: 10.1042/CS20210666. PMID: 34878105. Publication
Kopf A, Bunk B, Coldewey SM, Gunzer F, Riedel T, Schröttner P (2021) Identification and antibiotic profiling of Wohlfahrtiimonas chitiniclastica, an underestimated human pathogen. Front Microbiol. 2021 Sep 22;12:712775. doi: 10.3389/fmicb.2021.712775. eCollection 2021. PMID: 34630346. Publication
von Loeffelholz C, Coldewey SM, Birkenfeld AL (2021) A Narrative Review on the Role of AMPK on De Novo Lipogenesis in Non-Alcoholic Fatty Liver Disease: Evidence from Human Studies. Cells. 2021 Jul 19;10(7):1822. doi: 10.3390/cells10071822. PMID: 34359991. Publication
Press AT, Babic P, Hoffmann B, Müller T, Foo W, Hauswald W, Benecke J, Beretta M, Cseresnyés Z, Hoeppener S,
Nischang I, Coldewey SM, Gräler MH, Bauer R, Gonnert F, Gaßler N, Wetzker R, Figge MT, Schubert US, Bauer M (2021) Targeted delivery of a phosphoinositide 3-kinase inhibitor to restore organ function in sepsis. EMBO Mol Med. 2021 Oct 7;13(10):e14436. doi: 10.15252/emmm.202114436. Epub 2021 Sep 2. PMID: 34472699. Publication
Chung HY, Neu C, Wickel J, Kuckertz SL, Coldewey SM (2021) Neurofilament light chain in patients with COVID-19 and bacterial pneumonia. Ann Neurol. 2021 Jul;90(1):174-175. doi: 10.1002/ana.26135. Epub 2021 Jun 9. PMID: 34036618. Letter
König R, Kolte A, Ahlers O, Oswald M, Krauss V, Roell D, Sommerfeld O, Dimopoulos G, Tsangaris I, Antoniadou E, Jaishankar N, Bogatsch H, Löffler M, Rödel M, Garcia-Moreno M, Tuchscherr L, Sprung CL, Singer M, Brunkhorst F, Oppert M, Gerlach H, Claus RA, Coldewey SM, Briegel J, Giamarellos-Bourboulis EJ, Keh D, Bauer M (2021) Use of IFNγ/IL10 Ratio for Stratification of Hydrocortisone Therapy in Patients With Septic Shock. Front Immunol. 2021 Mar 9;12:607217. doi: 10.3389/fimmu.2021.607217. eCollection 2021. PMID: 33767693. Publication
Baumbach P, Schmidt-Winter C, Hoefer J, Derlien S, Best N, Herbsleb M, Coldewey SM (2020) A Pilot Study on the Association of Mitochondrial Oxygen Metabolism and Gas Exchange during Cardiopulmonary Exercise Testing: Is there a Mitochondrial Threshold? Front Med (Lausanne). 2020 Dec 21;7:585462. doi: 10.3389/fmed.2020.585462. eCollection 2020. PMID: 33409287. Publication
Nicklas JY, Diener O, Leistenschneider M, Sellhorn C, Schön G, Winkler M, Daum G, Schwedhelm E, Schröder J, Fisch M, Schmalfeldt B, Izbicki JR, Bauer M, Coldewey SM, Reuter DA, Saugel B (2020) Personalised haemodynamic management targeting baseline cardiac index in high-risk patients undergoing major abdominal surgery: a randomised single-centre clinical Trial. Br J Anaesth. 2020 Aug;125(2):122-132. doi: 10.1016/j.bja.2020.04.094. PMID: 32711724. Publication
Stallmach A, Kortgen A, Gonnert F, Coldewey SM, Reuken P, Bauer M (2020) Infliximab against severe COVID-19-induced cytokine storm syndrome with organ failure-a cautionary case series. Crit Care. 2020 Jul 17;24(1):444. doi: 10.1186/s13054-020-03158-0. PMID: 32680535. Publication
Gläser A, Hammerl F, Gräler MH, Coldewey SM, Völkner C, Frech MJ, Yang F, Luo J, Tönnies E, von Bohlen und Halbach O, Brandt N, Heimes D, Neßlauer A-M, Korenke GC, Owczarek-Lipska M, Neidhardt J, Rolfs A, Wree A, Witt M, Bräuer AU (2020) Identification of Brain-Specific Treatment Effects in NPC1 Disease by Focusing on Cellular and Molecular Changes of Sphingosine-1-Phosphate Metabolism. Int J Mol Sci. 2020 Jun 24;21(12):4502. doi: 10.3390/ijms21124502. PMID: 32599915. Publication
Coldewey SM, Neu C, Baumbach P, Scherag A, Goebel B, Ludewig K, Bloos F, Bauer M (2020) Identification of cardiovascular and molecular prognostic factors for the medium-term and long-term outcomes of sepsis (ICROS): protocol for a prospective monocentric cohort study. BMJ Open. 2020 Jun 23;10(6):e036527. doi: 10.1136/bmjopen-2019-036527. PMID: 32580988. Publication
Neu C, Lange AI, Wissuwa B, Coldewey SM (2020) Mikrozirkulationsstörung in der Sepsis. DIVI 2020; 11: 66–73, DOI 10.3238/DIVI.2020.0066-0073
Sobbe IV, Krieg N, Dennhardt S, Coldewey SM (2020) Involvement of NF-κB1 and the Non-Canonical NF-κB Signaling Pathway in the Pathogenesis of Acute Kidney Injury in Shiga-Toxin-2-Induced Hemolytic-Uremic Syndrome in Mice. Shock. 2021 Oct 1;56(4):573-581. doi: 10.1097/SHK.0000000000001558. PMID: 32433206. Publication
Neu C, Baumbach P, Plooij AK, Skitek K, Götze J, von Loeffelholz C, Schmidt-Winter C, Coldewey SM (2020) Non-Invasive Assessment of Mitochondrial Oxygen Metabolism in the Critically Ill Patient Using the Protoporphyrin IX‐Triplet State Lifetime Technique – a Feasibility Study. Front Immunol. 2020 May 7;11:757. doi: 10.3389/fimmu.2020.00757. eCollection 2020. PMID: 32457741. Publication
Zechendorf E, O'Riordan CE, Stiehler L, Wischmeyer N, Chiazza F, Collotta D, Denecke B, Ernst S, Müller-Newen G, Coldewey SM, Wissuwa B, Collino M, Simon TP, Schuerholz T, Stoppe C, Marx G, Thiemermann C, Martin L (2020) Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis. JCI Insight. 2020 Apr 23;5(8):e131571. doi: 10.1172/jci.insight.131571. PMID: 32213712. Publication
Stepanovska B, Lange AI, Schwalm S, Pfeilschifter J, Coldewey SM, Huwiler A (2020) Downregulation of S1P lyase improves barrier function in human cerebral microvascular endothelial cells following an inflammatory challenge. Int J Mol Sci. 2020 Feb 13;21(4):1240. doi: 10.3390/ijms21041240. PMID: 32069843. Publication
Sponholz C, Schuwirth C, Koenig L, Hoyer H, Coldewey SM, Schelenz C, Doenst T, Kortgen A, Bauer M (2020) Intraoperative reduction of vasopressors using processed electroencephalographic monitoring in patients undergoing elective cardiac surgery: a randomized clinical trial. J Clin Monit Comput. 2020 Feb;34(1):71-80. doi: 10.1007/s10877-019-00284-1. Epub 2019 Feb 19. PMID: 30784008. Publication
Coldewey, SM, Neu, C (2019) Dysfunktion von Herz, Kreislauf und Mitochondrien im septischen Schock: Physiologischer Winterschlaf oder metabolischer Albtraum? IntensivNews, Jahrgang 23, Ausgabe 4/2019
Dennhardt S, Finke KR, Huwiler A, Coldewey SM (2019) Sphingosine-1-phosphate promotes barrier-stabilizing effects in human microvascular endothelial cells via AMPK-dependent mechanisms. Biochim Biophys Acta Mol Basis Dis. 2019 Apr 1;1865(4):774-781. doi: 10.1016/j.bbadis.2018.12.022. Epub 2019 Jan 17. PMID: 30660683. Publication
Baumbach P, Neu C, Derlien S, Bauer M, Nisser M, Buder A, Coldewey SM (2019) A pilot study of exercise-induced changes in mitochondrial oxygen metabolism measured by a cellular oxygen metabolism monitor (PICOMET). Biochim Biophys Acta Mol Basis Dis. 2019 Apr 1;1865(4):749-758. doi: 10.1016/j.bbadis.2018.12.003. Epub 2018 Dec 26. PMID: 30593898. Publication
Bauer M, Coldewey SM, Leitner M, Löffler B, Weis S, Wetzker R (2018) Deterioration of Organ Function as a Hallmark in Sepsis: The Cellular Perspective. Front Immunol. 2018 Jun 26;9:1460. doi: 10.3389/fimmu.2018.01460. eCollection 2018. PMID: 29997622. Publication
Dennhardt S, Pirschel W, Wissuwa B, Daniel C, Gunzer F, Lindig S, Medyukhina A, Kiehntopf M, Rudolph WW, Zipfel PF, Gunzer M, Figge MT, Amann K, Coldewey SM (2018) Modeling Hemolytic-Uremic Syndrome: In-Depth Characterization of Distinct Murine Models Reflecting Different Features of Human Disease. Front Immunol. 2018 Jun 25;9:1459. doi: 10.3389/fimmu.2018.01459. eCollection 2018. PMID: 29988557. Publication
Wissuwa B, Heinemann SH, Bauer M, Coldewey SM (2018) Studies into Slo1 K+ channels and their ligand docosahexaenoic acid in murine sepsis to delineate off-target effects of immunonutrition. Life Sci. 2018 Jun 15;203:112-120. doi: 10.1016/j.lfs.2018.04.031. Epub 2018 Apr 21. PMID: 29684444. Publication
Meinel C, Spartà G, Dahse HM, Hörhold F, König R, Westermann M, Coldewey SM, Cseresnyés Z, Figge MT, Hammerschmidt S, Skerka C, Zipfel PF (2018) Streptococcus pneumoniae From Patients With Hemolytic Uremic Syndrome Binds Human Plasminogen via the Surface Protein PspC and Uses Plasmin to Damage Human Endothelial Cells. J Infect Dis. 2018 Jan 17;217(3):358-370. doi: 10.1093/infdis/jix305. PMID: 28968817. Publication
Weis S, Dickmann P, Pletz MW, Coldewey SM, Gerlach H, Bauer M (2017) Eine neue Definition führt zu neuen Konzepten. Dtsch Arztebl. 29-30: A1424-A1428, A6-A7.
Wöchtl B, Gunzer F, Gerner W, Gasse H, Koch M, Bagó Z, Ganter M, Weissenböck H, Dinhopl N, Coldewey SM, von Altrock A, Waldmann KH, Saalmüller A, Zimmermann K, Steinmann J, Kehrmann J, Klein-Hitpass L, Blom J, Ehricht R, Engelmann I, Hennig-Pauka I (2017) Comparison of clinical and immunological findings in gnotobiotic piglets infected with Escherichia coli O104:H4 outbreak strain and EHEC O157:H7. Gut Pathog. 2017 May 25;9:30. doi: 10.1186/s13099-017-0179-8. eCollection 2017. PMID: 28559930. Publication
Dickmann P, Scherag A, Coldewey SM, Sponholz C, Brunkhorst FM, Bauer M (2017) [Epistemology in the intensive care unit-what is the purpose of a definition? : Paradigm shift in sepsis research]. Anaesthesist. 2017 Aug;66(8):622-625. doi: 10.1007/s00101-017-0315-3. PMID: 28500500. Publication
Seidel RA, Claudel T, Schleser FA, Ojha NK, Westerhausen M, Nietzsche S, Sponholz C, Cuperus F, Coldewey SM, Heinemann SH, Pohnert G, Trauner M, Bauer M (2017) Impact of higher-order heme degradation products on hepatic function and hemodynamics. J Hepatol. 2017 Aug;67(2):272-281. doi: 10.1016/j.jhep.2017.03.037. Epub 2017 Apr 12. PMID: 28412296. Publication
Coldewey SM, Benetti E, Collino M, Pfeilschifter J, Sponholz C, Bauer M, Huwiler A, Thiemermann C (2016) Elevation of serum sphingosine-1-phosphate attenuates impaired cardiac function in experimental sepsis. Sci Rep. 2016 Jun 9;6:27594. doi: 10.1038/srep27594. PMID: 27277195.
Gobbetti T, Coldewey SM, Chen J, McArthur S, le Faouder P, Cenac N, Flower RJ, Thiemermann C, Perretti M (2014) Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis. Proc. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18685-90. doi: 10.1073/pnas.1410938111. Epub 2014 Dec 15. PMID: 25512512.
Coldewey SM, Thiemermann C (2014) Pleiotropic effects of atorvastatin in experimental sepsis: preservation of β1-adrenoreceptor signaling in the heart. Shock. 2014 May;41(5):458-9. doi: 10.1097/SHK.0000000000000154. PMID: 25133602. No abstract available.
Chen J, Chiazza F, Collino M, Patel NS, Coldewey SM, Thiemermann C (2014) Gender dimorphism of the cardiac dysfunction in murine sepsis: signalling mechanisms and age-dependency. PLoS One. 2014 Jun 19;9(6):e100631. doi: 10.1371/journal.pone.0100631. eCollection 2014. PMID: 24945834.
Coldewey SM, Rogazzo M, Collino M, Patel NS, Thiemermann C (2013) Inhibition of IκB kinase reduces the multiple organ dysfunction caused by sepsis in the mouse. Dis Model Mech. 2013 Jul;6(4):1031-42. doi: 10.1242/dmm.012435. Epub 2013 May 2. PMID: 23649820.
Coldewey SM, Khan AI, Kapoor A, Collino M, Rogazzo M, Brines M, Cerami A, Hall P, Sheaff M, Kieswich JE, Yaqoob MM, Patel NS, Thiemermann C (2013) Erythropoietin attenuates acute kidney dysfunction in murine experimental sepsis by activation of the β-common receptor. Kidney Int. 2013 Sep;84(3):482-90. doi: 10.1038/ki.2013.118. Epub 2013 Apr 17. PMID: 23594675.
Khan AI, Coldewey SM, Patel NS, Rogazzo M, Collino M, Yaqoob MM, Radermacher P, Kapoor A, Thiemermann C (2013) Erythropoietin attenuates cardiac dysfunction in experimental sepsis in mice via activation of the β-common receptor. Dis Model Mech. 2013 Jul;6(4):1021-30. doi: 10.1242/dmm.011908. Epub 2013 Mar 15. PMID: 23519033.
Jüttner B, Kröplin J, Coldewey SM, Witt L, Osthaus WA, Weilbach C, Scheinichen D (2008) Unsaturated long-chain fatty acids induce the respiratory burst of human neutrophils and monocytes in whole blood. Nutr Metab (Lond). 2008 Jul 14;5:19. doi: 10.1186/1743-7075-5-19. PMID: 18625045.
Kieckbusch H, Coldewey SM, Hollenhorst J, Haeseler G, Hillemanns P, Hertel H (2008) Patent blue sentinel node mapping in cervical cancer patients may lead to decreased pulse oximeter readings and positive methaemoglobin results. Eur J Anaesthesiol. 2008 May;25(5):365-8. doi: 10.1017/S0265021508003578. Epub 2008 Feb 13. PMID: 18272013.
Coldewey SM, Hartmann M, Schmidt DS, Engelking U, Ukena SN, Gunzer F (2007) Impact of the rpoS genotype for acid resistance patterns of pathogenic and probiotic Escherichia coli. BMC Microbiol. 2007 Mar 26;7:21. doi: 10.1186/1471-2180-7-21. PMID: 17386106.
Ukena SN, Westendorf AM, Hansen W, Rohde M, Geffers R, Coldewey S, Suerbaum S, Buer J, Gunzer F (2005) The host response to the probiotic Escherichia coli strain Nissle 1917: specific up-regulation of the proinflammatory chemokine MCP-1. BMC Med Genet. 6:43.