Publications

2020

von Müller C, Bulman F, Wagner L, Rosenberger D, Marolda A, Kurzai O, Eißmann P, Jacobsen ID, Perner B, Hemmerich P, Vylkova S (2020) Active neutrophil responses counteract Candida albicans burn wound infection of ex vivo human skin explants. Sci Rep 10(1), 21818.

Mirhakkak MH, Schäuble S, Klassert TE, Brunke S, Brandt P, Loos D, Uribe RV, Senne de Oliveira Lino F, Ni Y, Vylkova S, Slevogt H, Hube B, Weiss GJ, Sommer MOA, Panagiotou G (2020) Metabolic modeling predicts specific gut bacteria as key determinants for Candida albicans colonization levels. ISME J. doi: 10.1038/s41396-020-00848-z. Online ahead of print.

Wagner L, Bloos F, Vylkova S (2020) Bloodstream infection due to Enterobacter ludwigii, correlating with massive aggregation on the surface of a central venous catheter. Infection. doi: 10.1007/s15010-020-01482-9.

Kämmer P, McNamara S*, Wolf T, Conrad T, Allert S, Gerwien F, Hünniger K, Kurzai O, Guthke R, Hube B, Linde J, Brunke S (2020) Survival strategies of pathogenic Candida species in human blood show independent and specific adaptations. mBio 11(5), e02435-20.

Gerwien F, Dunker C, Brandt P, Garbe E, Jacobsen ID, Vylkova S (2020) Clinical Candida albicans vaginal isolates and a laboratory strain show divergent behaviors during macrophage interactions. mSphere 5(4), e00393-20.

Brandt P, Garbe E, Vylkova S (2020) Catch the wave: Metabolomic analyses in human pathogenic fungi. PLoS Pathog 16(8), e1008757. (Review)

Wagner L, Stielow JB, de Hoog GS, Bensch K, Schwartze VU, Voigt K, Alastruey-Izquierdo A, Kurzai O, Walther G (2020) A new species concept for the clinically relevant Mucor circinelloides complex. Persoonia 44, 67-97.

Böttcher B, Hoffmann B, Garbe E, Weise T, Cseresnyés Z, Brandt P, Dietrich S, Driesch D, Figge MT, Vylkova S (2020) The transcription factor Stp2 is important for Candida albicans biofilm establishment and sustainability. Front. Microbiol. 11:794.

Ruben S, Garbe E, Mogavero S, Albrecht-Eckardt D, Hellwig D, Häder A, Krüger T, Gerth K, Jacobsen ID, Elshafee O, Brunke S, Hünniger K, Kniemeyer O, Brakhage AA, Morschhäuser J, Hube B, Vylkova S, Kurzai O, Martin R. (2020) Ahr1 and Tup1 Contribute to the Transcriptional Control of Virulence-Associated Genes in Candida albicans. mBio. 11(2). pii: e00206-20. doi: 10.1128/mBio.00206-20.

Weise T, Böttcher B, Vylkova S. (2020) Bioflux Analysis. Protocols. doi:10.17504/protocols.io.bb7qirmw

2019

Garbe E & Vylkova S. (2019) Role of Amino Acid Metabolism in the Virulence of Human Pathogenic Fungi. Current Clinical Microbiology Reports. 6:108–119.

2017

Vylkova S (2017) Environmental pH modulation by pathogenic fungi as a strategy to conquer the host. PloS Pathogens1 3(2), e1006149.

Vylkova S, Lorenz MC (2017) Phagosomal neutralization by the fungal pathogen Candida albicans induces macrophage pyroptosis. Infect Immun 85(2). pii: e00832-16.

2016

Danhof HA, Vylkova S, Vesely EM, Ford AE, Gonzalez-Garay M, Lorenz MC (2016) Robust Extracellular pH Modulation by Candida albicans during Growth in Carboxylic Acids. mBio. 7(6).

2014

Vylkova S, Lorenz MC (2014) Modulation of phagosomal pH by Candida albicans promotes hyphal morphogenesis and requires Stp2p, a regulator of amino acid transport. PLoS Pathog 10(3), e1003995.

Previously

Vylkova S, Carman AJ, Danhof HA, Collette JR, Zhou H, Lorenz MC (2011) The fungal pathogen Candida albicans autoinduces hyphal morphogenesis by raising extracellular pH. MBio 2(3), e00055.

Miranda M, Bashi E, Vylkova S, Edgerton M, Slayman C, Rivetta A (2009) Conservation and dispersion of sequence and function in fungal TRK potassium transporters: focus on Candida albicans. FEMS Yeast Res 9(2):278-292.

Carman AJ, Vylkova S, Lorenz MC (2008) Role of acetyl coenzyme A synthesis and breakdown in alternative carbon source utilization in Candida albicans. Eukaryot Cell 7(10):1733-1741.

Vylkova S, Jang WS, Li W, Nayyar N, Edgerton M (2007) Histatin 5 initiates osmotic stress response in Candida albicans via activation of the Hog1 mitogen-activated protein kinase pathway. Eukaryot Cell 6(10):1876-1888.

Vylkova S, Nayyar N, Li W, Edgerton M (2007) Human beta-defensins kill Candida albicans in an energy-dependent and salt-sensitive manner without causing membrane disruption. Antimicrob Agents Chemother 51(1):154-161.

Vylkova S, Sun JN, Edgerton M (2007) The role of released ATP in killing Candida albicans and other extracellular microbial pathogens by cationic peptides. Purinergic Signal 3(1-2):91-97.

Vylkova S, Li XS, Berner JC, Edgerton M (2006) Distinct antifungal mechanisms: beta-defensins require Candida albicans Ssa1 protein, while Trk1p mediates activity of cysteine-free cationic peptides. Antimicrob Agents Chemother 50(1), 324-331.

Baev D, Rivetta A, Vylkova S, Sun JN, Zeng GF, Slayman CL, Edgerton M (2004) The TRK1 potassium transporter is the critical effector for killing of Candida albicans by the cationic protein, Histatin 5. J Biol Chem 279(53):55060-55072.

Baev D, Rivetta A, Li XS, Vylkova S, Bashi E, Slayman CL, Edgerton M (2003) Killing of Candida albicans by human salivary histatin 5 is modulated, but not determined, by the potassium channel TOK1. Infect Immun 71(6):3251-3260.

Dong J, Vylkova S, Li XS, Edgerton M (2003) Calcium blocks fungicidal activity of human salivary histatin 5 through disruption of binding with Candida albicans. J Dent Res 82(9):748-752.