Obituary Professor Eberhard Straube
We are deeply saddened to have learned that Professor Eberhard Straube, founding member of ZIK Septomics, passed away on August 19th, 2023. Professor Eberhard Straube was director of the Institute of …
Habilitation successfully completed
On September 8, Dr. rer. nat. Tilman Klassert, postdoc in the former ZIK Septomics research group Host Septomics (Head: Prof. Hortense Slevogt), held his demonstration lesson entitled "Microbiolog…
On September 6, 2023, Antonio Mestekemper successfully defended his medical dissertation. He conducted his work on "The role of renal and hepatic heme and iron homeostasis in the pathogenesis of e…
On July 4, 2023, Tina Müller, postdoc of the research group Translational Septomics, successfully defended her PhD thesis. She conducted her work on "Host Defense Mechanisms against Pathogens medi…
Genetic diversity impacts how our immune system reacts to different pathogens
Proband study published in Nature Communications
Monocytes are an essential part of our innate immune system and are of central importance in the defense against pathogens. These immune cells recognize pathogens based on pathogen-specific surface mo…
Philipp Brandt successfully defended his PhD thesis "Identification of unique mechanisms of nutrient acquisition in the major fungal pathogens Candida albicans and Candida auris” on June 2nd, 2023…
Welcome at Septomics, Slavica Janevska!
We are happy to welcome the new Junior Research Group "(Epi‑)Genetic Regulation of Fungal Virulence" of the Leibniz‑HKI headed by Dr. Slavica Janevska at Septomics. The group has moved into la…
Enrico Garbe successfully defended his PhD thesis "Nutrient acquisition and metabolic adaptation in the context of Candida albicans virulence” on March 1st, 2023. He conducted his PhD project in Dr. S…
The therapeutic use of Bruton tyrosine kinase inhibitors in Shiga toxin-mediated HUS.
New insights published on the therapeutic potential of Bruton tyrosine kinase inhibitors (BTKi) in Shiga toxin-induced hemolytic uremic syndrome.
Hemolytic uremic syndrome (HUS) is a serious disorder that can develop following oral infection with Shiga toxin (Stx)-producing Escherichia coli (STEC). In this case, HUS is clinically manifested by …
Gene switch of the Candida albicans toxin Candidalysin under the magnifying glass
Functional analysis of the ECE1 Promoter published in Microbiology Spectrum
Hyphae formation of Candia albicans, a key virulence trait of the human pathogenic fungus, is associated with the secretion of the cytotoxin Candidalysin. The toxic peptide contributes greatly to the …