A slimy matter

Bloodstream infections originating from a catheter contaminated with pathogens are not uncommon in intensive care units. Pathogens accumulate on the catheter surface and can form aggregates - so-called biofilms. These biofilms are very resistant to antibiotics and therefore difficult to treat. In this way, they often result in bloodstream infections and even can lead to sepsis. In a translational study, scientists of the JRG Host Fungal Interfaces, Lysett Wagner and Slavena Vylkova, are investigating the influence of blood components on biofilm formation on central venous catheters. Within the scope of the study, they have described in the journal ‘’Infections’’ that a catheter-associated bloodstream infection by the non-frequent opportunistic bacterial pathogen Enterobacter ludwigii is accompanied by a massive, slimy aggregate on the outside of a central venous catheter. The scientists thus draw attention to a rare pathogen that can cause catheter-associated biofilms and endanger the human health.

Publication:
Wagern L, Bloos F, Vylkova S (2020) Bloodstream infection due to Enterobacter ludwigii, correlating with massive aggregation on the surface of a central venous catheter, Infection. doi: 10.1007/s15010-020-01482-9.